{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T00:10:50Z","timestamp":1788567050016,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Periodontitis is a common, chronic inflammatory disease that relies heavily on effective daily oral hygiene for long\u2010term control. Light\u2010based therapies have demonstrated strong antibacterial potential; however, their effectiveness in regular home use remains unexplored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Two hundred stage I\u2013III periodontitis maintenance patients were randomized for supportive periodontal care (SPC) or SPC combined with adjunct home\u2010applied dual\u2010light therapy. Bleeding on probing (BOP), visible plaque index (VPI), and the number of sites with \u22654\u00a0mm periodontal probing depth (PPD) were measured at the baseline, at 3 and 6 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 200 randomized patients, 184 completed all visits. At baseline, the groups were similar for BOP, VPI, and pocket depth. At 3 and 6 months, adjunctive dual\u2010light therapy achieved lower BOP (12.6\u00a0\u00b1\u00a0\u00a00.7% and 12.0\u00a0\u00b1\u00a0\u00a00.8%) than SPC alone (17.8\u00a0\u00b1\u00a0\u00a00.8% and 17.3\u00a0\u00b1\u00a0\u00a01.0%);\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.0001 and\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.0002 and lower VPI (8.5 \u00b1\u00a00.7% and 9.7\u00a0\u00b1\u00a00.8%) vs. (13.3\u00a0\u00b1\u00a00.8% and 14.2\u00a0\u00b1\u00a01.0%);\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.0005 and 0.0142. The dual\u2010light group also had fewer sites with PPD\u00a0\u2265\u00a04\u00a0mm (5.6\u00a0\u00b1\u00a00.7 and 5.3\u00a0\u00b1\u00a00.6) vs. (7.6\u00a0\u00b1\u00a01.2 and 7.8\u00a0\u00b1\u00a00.9);\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.02 and\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.02.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Regularly home\u2010applied dual\u2010light therapy may represent a promising addition to existing home\u2010care strategies and a potential advance in adjunctive periodontal maintenance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Plain language summary<\/jats:title>\n                    <jats:p>Periodontitis is a common disease that damages the tissues supporting the teeth. Daily brushing and cleaning between the teeth are essential, but even with good routines, people can still develop plaque and gum inflammation. Light\u2010based treatments are known to eliminate plaque bacteria effectively, but until now, they have mostly been used in dental offices, and their potential for home use has not been tested. In the HOPE\u2010CP study, we enrolled 200 adults with periodontitis to receive routine supportive periodontal care. Half of them were randomized to use a light\u2010based antibacterial device to support their daily oral hygiene at home. After 3 and 6 months, those using the device had less gum bleeding, less visible plaque, and fewer sites with deeper periodontal pockets than those who used routine care alone. These results show that using a daily antibacterial light treatment at home may help people better control inflammation and maintain healthier gums between dental visits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jper.70082","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T11:08:09Z","timestamp":1772968089000},"page":"720-731","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A randomized controlled trial of home\u2010applied dual\u2010light photodynamic therapy during supportive periodontal care (HOPE\u2010CP study)"],"prefix":"10.1002","volume":"97","author":[{"given":"Saila","family":"Pakarinen","sequence":"first","affiliation":[{"name":"School of Rehabilitation and Examination Metropolia University of Applied Sciences  Helsinki Finland"},{"name":"Department of Oral and Maxillofacial Diseases Faculty of Medicine Department of Oral Diseases University of Helsinki, and Helsinki University Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannamari","family":"V\u00e4limaa","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Diseases Faculty of Medicine Department of Oral Diseases University of Helsinki, and Helsinki University Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna M.","family":"Heikkinen","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Technology University of Tampere  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marja","family":"Noponen","sequence":"additional","affiliation":[{"name":"Social Services, Healthcare and Rescue Services Division Oral Health Care  Helsinki Finland"},{"name":"Department of General Practice and Primary Health Care University of Helsinki (R.S.)  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