{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T23:53:31Z","timestamp":1780098811519,"version":"3.54.0"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,12,10]],"date-time":"2023-12-10T00:00:00Z","timestamp":1702166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2024,1]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>Head imaging is often performed in children with persistent dysphagia with aspiration to evaluate for Chiari malformations that may be associated with dysphagia. Unfortunately, the frequency of Chiari malformations or other head imaging abnormalities in children who aspirate is unknown. The goal of this study is to determine the frequency of head imaging abnormalities in children with evidence of aspiration or penetration on video fluoroscopic swallow study (VFSS).<\/jats:p><\/jats:sec>Setting<\/jats:title>Tertiary Children's Hospital.<\/jats:p><\/jats:sec>Methods<\/jats:title>We performed retrospective analysis of children with a diagnosis of aspiration evaluated at our center from January 2010 through April 2021. In this study, we included children with VFSS confirmed\u00a0aspiration or penetration, brain magnetic resonance imaging (MRI) performed at our center, and without known genetic, congenital craniofacial, or neurologic abnormalities.<\/jats:p><\/jats:sec>Results<\/jats:title>Of the 977 patients evaluated in our system during that time with a diagnosis of aspiration, 185 children met the inclusion criteria. Eight children were diagnosed with Chiari malformations (4.3%) and 94 head MRIs were abnormal (51.4%). There was no difference in VFSS findings (frequency of aspiration, penetration, penetration\u2010aspiration score, or recommended thickness of liquid) in children with a Chiari malformation versus other abnormalities or normal brain imaging. The majority of other non\u2010Chiari brain imaging abnormalities were nonspecific. There was no difference in VFSS findings in children with abnormal MRI findings versus normal MRI.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Brain imaging abnormalities are common in children who aspirate. Intervenable lesions are rare. Further studies are required to determine patients that will most likely benefit from brain imaging.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jpn3.12055","type":"journal-article","created":{"date-parts":[[2023,12,16]],"date-time":"2023-12-16T06:54:54Z","timestamp":1702709694000},"page":"52-56","source":"Crossref","is-referenced-by-count":1,"title":["Brain imaging abnormalities in children with dysphagia with aspiration: A retrospective study"],"prefix":"10.1002","volume":"78","author":[{"given":"Bhumi","family":"Patel","sequence":"first","affiliation":[{"name":"Indiana University School of Medicine Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Muston","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Pulmonology Allergy and Immunology Indiana University Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4468-4347","authenticated-orcid":false,"given":"Ryan T.","family":"Pitman","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Gastroenterology Indiana University Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2015.2266"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0b013e32834029de"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000381372"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2021.110874"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2014.06.004"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2016.06.019"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.110.6.1212"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2016.4735"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2023.103887"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.3171\/2010.3.PEDS09489"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/pq9.0000000000000123"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00009610"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199205000-00011"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.3171\/2011.5.PEDS1121"}],"container-title":["Journal of Pediatric Gastroenterology and Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jpn3.12055","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T03:06:41Z","timestamp":1712545601000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jpn3.12055"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,10]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1002\/jpn3.12055"],"URL":"https:\/\/doi.org\/10.1002\/jpn3.12055","archive":["Portico"],"relation":{},"ISSN":["0277-2116","1536-4801"],"issn-type":[{"value":"0277-2116","type":"print"},{"value":"1536-4801","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,10]]}}}