{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:56:45Z","timestamp":1787317005575,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T00:00:00Z","timestamp":1703635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Pediatric patients diagnosed with inflammatory bowel disease (IBD) are at risk of suboptimal peak bone mass attainment. This study aimed to understand rates of bone health screening adherence, describe factors associated with dual\u2010energy X\u2010ray absorptiometry (DXA) acquisition, and identify factors associated with abnormal DXA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a retrospective cohort study of pediatric IBD patients over a 10\u2010year time frame. We included IBD patients (2\u201320 years of age) enrolled in ImproveCareNow and excluded patients with primary metabolic bone disease. Time\u2010to\u2010event methods and multivariable logistic regression were employed to identify factors associated with DXA acquisition and abnormal DXA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In 676 patients, 464 (68.63%) pediatric patients with IBD had a risk factor for low bone mineral density (BMD); 137 (29.53%) underwent an initial DXA scan. Quiescent disease was significantly associated with a reduced likelihood of DXA (hazard ratio [HR]: 0.48; 95% confidence interval [CI]: 0.24\u20130.97), while weight\n                      <jats:italic>z<\/jats:italic>\n                      \u2010score &lt;\u22122 was significantly associated with DXA performance (HR: 2.07; 95% CI: 1.08\u20133.98). Abnormal DXA results (BMD\n                      <jats:italic>z<\/jats:italic>\n                      \u2010score \u2264\u22121) occurred in 59 (35.54%) individuals. After adjusting for visit diagnosis, delayed puberty, severe disease course, 6 months or greater of steroid exposure, and history of fracture, BMI\n                      <jats:italic>z<\/jats:italic>\n                      \u2010score &lt;\u22121 (odds ratio: 5.45; 95% CI: 2.41\u201312.33) was associated with abnormal DXA.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      DXA screening occurred in less than one\u2010third of eligible pediatric IBD patients. Compliance was more common in patients with a weight\n                      <jats:italic>z<\/jats:italic>\n                      \u2010score &lt;\u22122 and less common in those with quiescent disease. BMI strongly predicted abnormal DXA results when adjusting for risk factors for abnormal BMD.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jpn3.12107","type":"journal-article","created":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T06:26:15Z","timestamp":1703658375000},"page":"252-260","source":"Crossref","is-referenced-by-count":3,"title":["Bone health screening practices with dual\u2010energy X\u2010ray absorptiometry and prediction of abnormal results in pediatric inflammatory bowel disease"],"prefix":"10.1002","volume":"78","author":[{"given":"Ryan","family":"Morrow","sequence":"first","affiliation":[{"name":"Children's Hospital Colorado Digestive Health Institute Aurora Colorado USA"},{"name":"Department of Pediatrics, School of Medicine University of Colorado Anschutz Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin F.","family":"de Zoeten","sequence":"additional","affiliation":[{"name":"Children's Hospital Colorado Digestive Health Institute Aurora Colorado USA"},{"name":"Department of Pediatrics, School of Medicine University of Colorado Anschutz Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, School of Medicine University of Colorado Anschutz Aurora Colorado USA"},{"name":"Section of Pediatric Endocrinology Children's Hospital Colorado Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille","family":"Chun","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, School of Medicine University of Colorado Anschutz Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank I.","family":"Scott","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology University of Colorado Anschutz Medical Campus Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e31821988a3"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2014.01.007"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2014.01.073"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2007.01.002"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000002911"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11657-021-00945-2"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e31825959b8"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0b013e318281f5b5"},{"key":"e_1_2_7_10_1","unstructured":"IMPROVECARENOW. 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