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This study examined differences in diagnosis age, biomarkers of disease severity, and anthropometrics with sociodemographic factors in a pediatric IBD cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Pediatric IBD patients (<jats:italic>n<\/jats:italic>\u2009=\u2009114) and their parents\/caregivers were enrolled from the Children's of Alabama Pediatric IBD Clinic in Birmingham, Alabama. Primary analyses examined associations of child race and ethnicity, parental income, parental education, single\u2010parent household status, insurance type, and distance to a tertiary pediatric gastroenterology referral center with diagnosis age. Secondary analyses examined differences in biomarker levels, height, and body mass index at the time of diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Racial and ethnic minority children were diagnosed at an older age compared to Non\u2010Hispanic White children (14.4\u2009\u00b1\u20090.40 vs. 11.7\u2009\u00b1\u20090.38 years; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and this trend was robust to adjustment with other sociodemographic variables. Parental attainment of a college education attenuated the link between minority race and ethnicity and the likelihood of older age at diagnosis, while other sociodemographic variables had no moderating effect. Racial and ethnic minority children were 5.7 times more likely to have clinically elevated erythrocyte sedimentation rate at diagnosis compared to Non\u2010Hispanic White children (<jats:italic>p<\/jats:italic>\u2009=\u2009.024).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These results suggest that child race and ethnicity may exert a primary effect on the age at diagnosis with pediatric\u2010onset IBD. This study highlights the need for further research on racial and ethnic disparities to promote health equity in pediatric\u2010onset IBD.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jpn3.12131","type":"journal-article","created":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T13:29:10Z","timestamp":1706534950000},"page":"634-643","source":"Crossref","is-referenced-by-count":6,"title":["Racial and ethnic differences in diagnosis age and blood biomarkers in a pediatric inflammatory bowel disease cohort"],"prefix":"10.1002","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3538-852X","authenticated-orcid":false,"given":"Keri M.","family":"Kemp","sequence":"first","affiliation":[{"name":"Cardio\u2010Renal Physiology and Medicine Section, Division of Nephrology, Department of Medicine, Heersink School of Medicine University of Alabama at Birmingham Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pooja K.","family":"Nagaraj","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Gastroenterology, Heersink School of Medicine University of Alabama at Birmingham Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catheryn A.","family":"Orihuela","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Alabama at Birmingham Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin G.","family":"Lorenz","sequence":"additional","affiliation":[{"name":"Department of Research Pathology Genentech South San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig L.","family":"Maynard","sequence":"additional","affiliation":[{"name":"Department of Pathology, Heersink School of Medicine University of Alabama at Birmingham Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer S.","family":"Pollock","sequence":"additional","affiliation":[{"name":"Cardio\u2010Renal Physiology and Medicine Section, Division of Nephrology, Department of Medicine, Heersink School of Medicine University of Alabama at Birmingham Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Traci","family":"Jester","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Gastroenterology, Heersink School of Medicine University of Alabama at Birmingham Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.j2083"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.06.081"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.06.079"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2021.12.282"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-021-02496-4"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjaa197"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-021-01938-8"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000001257"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756284819827692"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000835"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2022.03.011"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000001204"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.192"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-22429-z"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.202"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-020-06434-9"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000001046"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2008.07.032"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(98)70187-8"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izz225"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2007.04.004"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1536-4801.2003.tb12072.x"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.21105\/joss.03544"},{"key":"e_1_2_8_25_1","unstructured":"HijmansR2022.Geosphere: spherical trigonometry. 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