{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T08:16:09Z","timestamp":1788336969242,"version":"build-2803163510"},"reference-count":45,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T00:00:00Z","timestamp":1712102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To identify and distinguish between racial and socioeconomic disparities in age at hepatology care, diagnosis, access to surgical therapy, and liver transplant\u2010free survival in patients with biliary atresia (BA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Single\u2010center retrospective cohort study of 69 BA patients from 2010 to 2021. Patients were grouped into White and non\u2010White cohorts. The socioeconomic milieu was analyzed utilizing neighborhood deprivation index, a census tract\u2010based calculation of six socioeconomic variables. The primary outcomes of this study were timing of the first hepatology encounter, surgical treatment with hepatic portoenterostomy (HPE),\u00a0and survival with native liver (SNL) at 2\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients were 55% male and 72% White. White patients were referred at a median of 34 days (interquartile range [IQR]: 17\u201365) vs. 67 days (IQR: 42\u2013133; <jats:italic>p<\/jats:italic>\u2009=\u20090.001) in non\u2010White patients. White infants were more likely to undergo HPE (42\/50 patients; 84%) compared to non\u2010White (10\/19; 53%), odds ratio (OR) 4.73 (95% confidence interval: 1.46\u201315.31; <jats:italic>p<\/jats:italic>\u2009=\u20090.01). Independent of race, patients exposed to increased neighborhood\u2010level deprivation were less likely to receive HPE (OR: 0.49, <jats:italic>p<\/jats:italic>\u2009=\u20090.04) and achieve SNL (OR: 0.54, <jats:italic>p<\/jats:italic>\u2009=\u20090.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Racial and socioeconomic disparities are independently associated with timely BA diagnosis, access to surgical treatment, and transplant\u2010free survival. Public health approaches to improve screening for pathologic jaundice in infants of diverse racial backgrounds and to test and implement interventions for socioeconomically at\u2010risk families are needed.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jpn3.12197","type":"journal-article","created":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T09:32:52Z","timestamp":1712136772000},"page":"1038-1046","source":"Crossref","is-referenced-by-count":9,"title":["Distinct effects of racial and socioeconomic disparities on biliary atresia diagnosis and outcome"],"prefix":"10.1002","volume":"78","author":[{"given":"Julie","family":"Bonn","sequence":"first","affiliation":[{"name":"Division of Pediatric Gastroenterology, Hepatology &amp; Nutrition Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Gamm","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology, Hepatology &amp; Nutrition Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Ambrosino","sequence":"additional","affiliation":[{"name":"Department of Surgery Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah H.","family":"Orkin","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology, Hepatology &amp; Nutrition Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Taylor","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology, Hepatology &amp; Nutrition Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0327-1378","authenticated-orcid":false,"given":"Anna L.","family":"Peters","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology, Hepatology &amp; Nutrition Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA"},{"name":"Department of Pediatrics University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29905"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2022.10.050"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181633562"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.11.058"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000002446"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2007.05.051"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-1949"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001334"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2022-058859"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-1869"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2019.13321"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(95)90345-3"},{"key":"e_1_2_8_13_2","unstructured":"discussion1080\u20101071."},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2001.25761"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001887"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.04.001"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23607"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2018.11.008"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.15786"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32106"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16529"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000003157"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000002527"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000755"},{"key":"e_1_2_8_25_1","unstructured":"BrokampC. 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