{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T06:10:24Z","timestamp":1781244624802,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Using high resolution impedance manometry (HRIM), this study characterized the esophago\u2010gastric junction (EGJ) dynamics in children with esophageal atresia (EA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Esophageal HRIM was performed in patients with EA aged less than 18 years. Objective motility patterns were analyzed, and EGJ data reported. Controls were pediatric patients without EA undergoing investigations for consideration of fundoplication surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010five patients (M:F\u2009=\u200943:32, median age 1 year 3 months [3 months\u201317 years 4 months]) completed 133 HRIM studies. The majority (64\/75, 85.3%) had EA with distal tracheo\u2010esophageal fistula. Compared with controls, liquid swallows were poorer in patients with EA, as evident by significant differences in distension pressure emptying and bolus flow time (BFT). The integrated relaxation pressure for thin liquid swallows was significantly different between EA types, as well as when comparing patients with EA with and without previous esophageal dilatations. The BFT for solid swallows was significantly different when compared with\u00a0EA types.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We have utilized HRIM in patients with EA to demonstrate abnormalities in their long\u2010term EGJ function. These abnormalities correlate with poorer esophageal compliance and reduced esophageal peristalsis across the EGJ. Understanding the EGJ function in patients with EA will allow us to tailor long\u2010term management to specific patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jpn3.12213","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T10:50:09Z","timestamp":1713264609000},"page":"1225-1233","source":"Crossref","is-referenced-by-count":5,"title":["Esophago\u2010gastric junction findings on high resolution impedance manometry in children with esophageal atresia"],"prefix":"10.1002","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4504-4969","authenticated-orcid":false,"given":"Sharman P.","family":"Tan Tanny","sequence":"first","affiliation":[{"name":"Department of Paediatric Surgery The Royal Children's Hospital Parkville Victoria Australia"},{"name":"F. Douglas Stephens Surgical Research Group Murdoch Children's Research Institute Parkville Victoria Australia"},{"name":"Department of Paediatrics The University of Melbourne Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas D.","family":"Senior","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery The Royal Children's Hospital Parkville Victoria Australia"},{"name":"F. Douglas Stephens Surgical Research Group Murdoch Children's Research Institute Parkville Victoria Australia"},{"name":"Department of Paediatrics The University of Melbourne Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assia","family":"Comella","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery The Royal Children's Hospital Parkville Victoria Australia"},{"name":"F. Douglas Stephens Surgical Research Group Murdoch Children's Research Institute Parkville Victoria Australia"},{"name":"Monash Medical School Monash University Clayton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"McCall","sequence":"additional","affiliation":[{"name":"Department of Human Physiology Flinders University Bedford Park South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Hutson","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery The Royal Children's Hospital Parkville Victoria Australia"},{"name":"F. 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