{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:47:02Z","timestamp":1789681622236,"version":"4.0.1"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,7,20]],"date-time":"2024-07-20T00:00:00Z","timestamp":1721433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>In pediatric patients with intestinal failure (IF) due to short bowel syndrome (SBS), we hypothesized that young children, those with shorter residual small bowel and those with congenital malrotation of the bowel would be more likely to undergo pan\u2010enteroscopy. We aimed to determine the feasibility and diagnostic yield of pan\u2010enteroscopy in this cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a single\u2010center, retrospective study of pediatric patients with IF due to SBS who had undergone at least one GI endoscopic evaluation between January 1, 2018 and January 1, 2023.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A pan\u2010enteroscopy might have been possible in 381 of the 431 procedures (206 patients) reviewed. Forty\u2010four (21%) patients underwent 54 pan\u2010enteroscopies. Children with a residual bowel length &lt;35\u2009cm had higher odds of undergoing pan\u2010enteroscopy (odds ratio [OR] 3.72, 95% confidence interval [CI] [1.32, 10.48], <jats:italic>p<\/jats:italic>\u2009=\u20090.01), as did patients with periprocedural glucagon\u2010like peptide 2 (GLP\u20102) analog use (OR 4.30, 95% CI [1.24, 14.95], <jats:italic>p<\/jats:italic>\u2009=\u20090.02). Patients with diagnoses other than necrotizing enterocolitis (NEC) tended to be more likely to achieve a pan\u2010enteroscopy (OR 2.73, 95% CI [0.95,7.88], <jats:italic>p<\/jats:italic>\u2009=\u20090.06). Evidence of gross and histopathologic abnormalities were found in 77.8% and 78% of the procedures, respectively. No complications were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In a large cohort of children with SBS, pan\u2010enteroscopy was successfully performed in 14.2% of the procedures and microscopic abnormalities were common. Shorter residual bowel length, underlying diagnoses of non\u2010NEC, and GLP\u20102 analog use were generally associated with successful pan\u2010enteroscopy, independent of age and several other factors. These data suggest that pan\u2010enteroscopy is feasible and of high\u2010yield in a subset of patients with SBS.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jpn3.12316","type":"journal-article","created":{"date-parts":[[2024,7,20]],"date-time":"2024-07-20T11:20:24Z","timestamp":1721474424000},"page":"915-923","source":"Crossref","is-referenced-by-count":1,"title":["Performance of pan\u2010enteroscopy in children with intestinal failure due to short bowel syndrome: A single\u2010center retrospective study"],"prefix":"10.1002","volume":"79","author":[{"given":"Jonathan A.","family":"Salazar","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Boston Children's Hospital Boston Massachusetts USA"},{"name":"Center for Advanced Intestinal Rehabilitation and Center for Nutrition, Boston Children's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Chan","sequence":"additional","affiliation":[{"name":"Institutional Centers for Clinical and Translational Research (ICCTR) Boston Children's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enju","family":"Liu","sequence":"additional","affiliation":[{"name":"Institutional Centers for Clinical and Translational Research (ICCTR) Boston Children's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima","family":"Hamroud","sequence":"additional","affiliation":[{"name":"Gastroenterology Procedure Unit Boston Children's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit S.","family":"Grover","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Boston Children's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor L.","family":"Fox","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Boston Children's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter D.","family":"Ngo","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Boston Children's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lissette","family":"Jimenez","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Boston Children's Hospital Boston Massachusetts USA"},{"name":"Center for Advanced Intestinal Rehabilitation and Center for Nutrition, Boston Children's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher P.","family":"Duggan","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Boston Children's Hospital Boston Massachusetts USA"},{"name":"Center for Advanced Intestinal Rehabilitation and Center for Nutrition, Boston Children's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1785-6123","authenticated-orcid":false,"given":"Alexandra N.","family":"Carey","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Boston Children's Hospital Boston Massachusetts USA"},{"name":"Center for Advanced Intestinal Rehabilitation and Center for Nutrition, Boston Children's Hospital Boston Massachusetts 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