{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T18:56:49Z","timestamp":1791917809285,"version":"4.3.4"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the features of multichannel intraluminal impedance and pH monitoring (MII\u2010pH) tracings in children with cerebral palsy (CP) and children without CP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Multicenter, retrospective, analytical study. We examined tracings of children aged 1 to 15 years old, evaluated from May 2017 to January 2024. Population included two groups: Group 1 consisted of children with CP, while control group comprised children without CP who had extra\u2010digestive symptoms suggestive of gastroesophageal reflux disease (GERD) but normal MII\u2010pH results. Quantitative data were analyzed using analysis of variance and <jats:italic>t<\/jats:italic> tests. Qualitative data were analyzed using contingency tables and chi\u2010square tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We studied 245 children. CP group included 110 children with a mean age of 5.71 years (standard deviation [SD]\u2009\u00b1\u20094.24), while control group included 135 children with a mean age of 5.73 years (SD\u2009\u00b1\u20093.39). The CP group had fewer reflux episodes (<jats:italic>p<\/jats:italic>\u2009=\u20090.0015), slower mean acid clearance time (<jats:italic>p<\/jats:italic>\u2009=\u20090.04), lower mean baseline impedance and mean nocturnal baseline impedance (<jats:italic>p<\/jats:italic>\u2009=\u20091.82e\u221207 and <jats:italic>p<\/jats:italic>\u2009=\u20097.50e\u221207).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Children with CP have fewer reflux episodes and longer acid clearance times compared with children without CP. Prospective studies including esophagogastroduodenoscopy findings are needed to establish MII\u2010pH reference values in children with CP.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jpn3.70058","type":"journal-article","created":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:28:57Z","timestamp":1746577737000},"page":"125-130","source":"Crossref","is-referenced-by-count":3,"title":["Analysis of multichannel intraluminal impedance and pH monitoring values in children with cerebral palsy: A comparative multicenter study"],"prefix":"10.1002","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3505-1294","authenticated-orcid":false,"given":"Cristina","family":"Lorenzo","sequence":"first","affiliation":[{"name":"Hospital Sor Maria Ludovica La Plata Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Zubiri","sequence":"additional","affiliation":[{"name":"Hospital Sor Maria Ludovica La Plata Buenos Aires 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