{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T04:24:26Z","timestamp":1783052666974,"version":"3.54.6"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Over 40% of children with Crohn's disease (CD) develop perianal lesions (skin tags and\/or fissures), which are associated with the risk of perianal fistula. It is unknown how reliably perianal symptoms predict perianal lesions. We recruited pediatric patients with CD who were undergoing colonoscopy for clinical indications. Patients self\u2010reported recent perianal symptoms. We retrospectively reviewed the perianal exam documented on colonoscopy reports and in the electronic health record to obtain details of perianal lesions if present. Thirty\u2010three patients were included: median age 15.6 years (interquartile range 12.9\u201317.5), 27% female, 80% White. There was no association between any perianal symptom and the presence or absence of any perianal lesion (<jats:italic>p<\/jats:italic>\u2009=\u20090.85), suggesting the presence or absence of perianal pain and\/or anal discharge does not predict whether a patient with CD has perianal lesions. This raises the importance of perianal examination, regardless of symptoms, for identifying perianal lesions early and enabling treatment aimed at preventing perianal fistula development in patients with CD.<\/jats:p>","DOI":"10.1002\/jpn3.70071","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:39:15Z","timestamp":1747190355000},"page":"69-73","source":"Crossref","is-referenced-by-count":1,"title":["Reliability of patient\u2010reported pain and discharge for predicting perianal lesions in pediatric Crohn's disease"],"prefix":"10.1002","volume":"81","author":[{"given":"Blake I.","family":"Hardin","sequence":"first","affiliation":[{"name":"University of Michigan Medical School Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew A. M.","family":"Singer","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology, C.S. Mott Children's Hospital, Michigan Medicine University of Michigan Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuemein J.","family":"Mar","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology, C.S. Mott Children's Hospital, Michigan Medicine University of Michigan Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George M.","family":"Zacur","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology, C.S. Mott Children's Hospital, Michigan Medicine University of Michigan Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally J.","family":"Eder","sequence":"additional","affiliation":[{"name":"Susan B. Meister Child Health Evaluation and Research Center, Michigan Medicine University of Michigan Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelley Rose","family":"French","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology, C.S. Mott Children's Hospital, Michigan Medicine University of Michigan Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4857-6098","authenticated-orcid":false,"given":"Jeremy","family":"Adler","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology, C.S. Mott Children's Hospital, Michigan Medicine University of Michigan Ann Arbor Michigan USA"},{"name":"Susan B. Meister Child Health Evaluation and Research Center, Michigan Medicine University of Michigan Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001447"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izz056"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.20767"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.5152\/tjg.2021.191034"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000492921"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.04.060"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.07.038"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2015.117"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000000754"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izaa307"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.20458"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-199703000-00004"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.7378"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2022.06.016"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000002119"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izy015"}],"container-title":["Journal of Pediatric Gastroenterology and Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jpn3.70071","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T12:12:01Z","timestamp":1754914321000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jpn3.70071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,13]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/jpn3.70071"],"URL":"https:\/\/doi.org\/10.1002\/jpn3.70071","archive":["Portico"],"relation":{},"ISSN":["0277-2116","1536-4801"],"issn-type":[{"value":"0277-2116","type":"print"},{"value":"1536-4801","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,13]]}}}