{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T05:10:30Z","timestamp":1771305030480,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T00:00:00Z","timestamp":1750982400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T00:00:00Z","timestamp":1750982400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Children with end\u2010stage liver disease (ESLD) are at risk for complications including serious bacterial infections (SBI). We used the linkage of the Scientific Registry of Transplant Recipients (SRTR) and Pediatric Health Information System (PHIS) databases to examine frequency and morbidity of SBI and identify patient\u2010specific risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We identified children listed for liver transplant between 2003 and 2019 who were hospitalized before transplant. Hospitalizations were characterized by SBI status using International Classification of Diseases (ICD) codes and healthcare utilization was compared using Chi\u2010square and t tests. Univariate and multivariate logistic regression were performed to identify patient variables associated with pre\u2010transplant SBI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 1849 patients had 7601 hospitalizations and the majority (85%) were without SBI. Hospitalizations with SBI had longer length of stay (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and greater likelihood of needing therapies in the intensive care (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Almost one\u2010third (32%) had hospitalization with SBI; in multivariate analysis, those with ascites (odds ratio [OR] 1.54 95% confidence interval [CI] 1.16\u20132.03) and nonprivate insurance (OR 1.40 95% CI 1.10\u20131.78) had higher odds of SBI. Patients with SBI had longer time on the waiting list (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.023) despite being more likely to have approved exception (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Despite experiencing a life\u2010threatening complication of ESLD, patients with SBI do not undergo more expeditious transplant. They are more likely to have approved exception requests but have longer waitlist time. The current organ allocation system does not effectively prioritize these high\u2010risk patients. SBI risk varies by insurance status, highlighting ongoing health disparities in pediatric transplantation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jpn3.70130","type":"journal-article","created":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T05:13:04Z","timestamp":1751001184000},"page":"634-643","source":"Crossref","is-referenced-by-count":0,"title":["What are we waiting for: Serious bacterial infections in children prior to liver transplant are associated with high morbidity but not expedited transplant"],"prefix":"10.1002","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8612-7165","authenticated-orcid":false,"given":"Bridget A.","family":"Whitehead","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition, Feinberg School of Medicine, Ann &amp; Robert H. Lurie Children's Hospital of Chicago Northwestern University Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Swati","family":"Antala","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hepatology Icahn School of Medicine at Mount Sinai, Mount Sinai Kravis Children's Hospital New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna M.","family":"Banc\u2010Husu","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Baylor College of Medicine Texas Children's Hospital Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katie","family":"Neighbors","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition, Feinberg School of Medicine, Ann &amp; Robert H. Lurie Children's Hospital of Chicago Northwestern University Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin A.","family":"Godown","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Cardiology Vanderbilt University School of Medicine Nashville Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matt","family":"Hall","sequence":"additional","affiliation":[{"name":"Children's Hospital Association Lenexa Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cary","family":"Thurm","sequence":"additional","affiliation":[{"name":"Children's Hospital Association Lenexa Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah A.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition University of Colorado School of Medicine, Children's Hospital Colorado Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Estella M.","family":"Alonso","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition, Feinberg School of Medicine, Ann &amp; Robert H. Lurie Children's Hospital of Chicago Northwestern University Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.24640"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14216"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.12.005"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2017.19"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.06.019"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cld.2021.01.006"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.12021"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.10.003"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2013.07.044"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.13379"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.15203"},{"key":"e_1_2_9_13_1","unstructured":"OPTN. 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