{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T03:26:34Z","timestamp":1788405994996,"version":"build-2803163510"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Endoscopic mucosal resection (EMR) is well established in adult gastroenterology but remains underutilized in pediatrics due to limited data, training opportunities, and equipment. This study presents a 10\u2010year, single\u2010center experience with conventional hot and cold snare EMR, band\u2010assisted (B\u2010EMR), and underwater EMR (U\u2010EMR) techniques in pediatric patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective review was conducted of all EMR procedures performed in patients under 21 years of age between 2015 and 2025 at a tertiary care children's hospital. Data on patient demographics, lesion characteristics, procedural details, pathology, and outcomes were collected and analyzed descriptively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty EMRs were performed in 18 patients (mean age 17.1 years, range 3\u201320). The most common underlying diagnoses included familial adenomatous polyposis (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20097), sporadic mucosal polyps (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20094), subepithelial lesions (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20094), juvenile polyposis syndrome (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20092), Peutz\u2010Jeghers syndrome (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091), and Lynch syndrome (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091). Lesions ranged from 6 to 80\u2009mm and were located throughout the gastrointestinal tract, most commonly in the colon (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20099), duodenum (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20095), and esophagus (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20093). Techniques included hot snare EMR (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20099), cold snare EMR (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20096), B\u2010EMR (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20094), and U\u2010EMR (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091). Complete resection was achieved in 95% of cases, with one incomplete resection requiring surgical management for adenocarcinoma. B\u2010EMR was safely applied to subepithelial lesions. No delayed complications occurred.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>EMR is feasible, safe, and effective in pediatric patients for both mucosal and subepithelial lesions. Broader adoption in pediatric practice will require expanded training, multidisciplinary collaboration, and development of pediatric\u2010specific guidelines. These findings support EMR as a valuable therapeutic option in complex pediatric gastrointestinal disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jpn3.70194","type":"journal-article","created":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T05:47:34Z","timestamp":1755064054000},"page":"1311-1317","source":"Crossref","is-referenced-by-count":4,"title":["Pediatric endoscopic mucosal resection: A 10\u2010year single\u2010center experience"],"prefix":"10.1002","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3048-5662","authenticated-orcid":false,"given":"Brett J.","family":"Hoskins","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition Indiana University School of Medicine, Riley Hospital for Children at IU Health Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared M.","family":"Grabau","sequence":"additional","affiliation":[{"name":"Department of Medicine Marian University Tom and Julie Wood College of Osteopathic Medicine Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas K.","family":"Rex","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology and Hepatology Indiana University School of Medicine Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-310249"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.12.018"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000003275"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2017.0633"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0000000000000265"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000002100"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000031072"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e3181956e0c"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000002059"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2023.12.007"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2021.07.044"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-022-09688-8"}],"container-title":["Journal of Pediatric Gastroenterology and Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jpn3.70194","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jpn3.70194","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jpn3.70194","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T03:34:27Z","timestamp":1780025667000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jpn3.70194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,12]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/jpn3.70194"],"URL":"https:\/\/doi.org\/10.1002\/jpn3.70194","archive":["Portico"],"relation":{},"ISSN":["0277-2116","1536-4801"],"issn-type":[{"value":"0277-2116","type":"print"},{"value":"1536-4801","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,12]]}}}