{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T17:48:48Z","timestamp":1784310528444,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T00:00:00Z","timestamp":1769472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T00:00:00Z","timestamp":1769472000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We retrospectively evaluated the effectiveness of budesonide orodispersible tablets (BOT) in children with eosinophilic esophagitis (EoE) followed up at our center. A total of 17 children were treated with BOT 0.5\u2009mg twice daily after a median time from diagnosis of 16 months (interquartile range [IQR]: 11\u201328.5). Previous treatments included proton\u2010pump inhibitors, food elimination diets, and topical swallowed corticosteroids (TSC). After 3 months, 11\/17 (65%) patients were in clinical remission. 8\/17 (47%) patients repeated an endoscopy after a median time of 11.5 months (6.75\u201316.75 IQR); 6\/8 (75%) were in endoscopic remission and 7\/8 (87.5%) achieved histological remission. Eosinophils count at histology significantly decreased from baseline (30 [15\u201350 IQR] to 6 [6\u20139 IQR],\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.03]. 3\/4 (75%) patients who previously failed TSC achieved complete remission on BOT. After a median follow\u2010up of 12.5 months (6.25\u201321 IQR), 11\/17 (65%) patients were still on BOT treatment, and 9\/11 (82%) were in clinical remission. No adverse events were reported.\n                  <\/jats:p>","DOI":"10.1002\/jpn3.70359","type":"journal-article","created":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T10:33:05Z","timestamp":1769509985000},"page":"1088-1093","source":"Crossref","is-referenced-by-count":1,"title":["Real\u2010world experience of budesonide orodispersible tablets in pediatric eosinophilic esophagitis"],"prefix":"10.1002","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6357-9273","authenticated-orcid":false,"given":"Saverio","family":"Pochesci","sequence":"first","affiliation":[{"name":"Department of Paediatric Gastroenterology, Hepatology and Nutrition Royal Hospital for Children &amp; Young People Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilo","family":"Maza Angulo","sequence":"additional","affiliation":[{"name":"Amsterdam UMC Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Grant","sequence":"additional","affiliation":[{"name":"Dietetics Department Royal Hospital for Children &amp; Young People Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard K.","family":"Russell","sequence":"additional","affiliation":[{"name":"Department of Paediatric Gastroenterology, Hepatology and Nutrition Royal Hospital for Children &amp; Young People Edinburgh UK"},{"name":"Child Life and Health, University of Edinburgh Royal Hospital for Children &amp; Young People Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2014.01.023"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13441"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-017-8665-9"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2017.10.003"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpn3.12188"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000507571"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.09.020"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2018.05.045"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.70197"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365521.2024.2395865"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.07.039"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.03.025"},{"key":"e_1_2_7_14_1","first-page":"S","article-title":"Budesonide oral suspension is effective and safe as induction treatment of eosinophilic esophagitis in children and adolescents: results from the randomized, double\u2010blind, placebo\u2010controlled induction phase of a multicenter pediatric trial (PEDEOS\u20101)","author":"Lucendo AJ","year":"2025","journal-title":"Gastroenterology"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2015.11.004"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.04.022"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.06.020"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000003449"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpn3.70106"}],"container-title":["Journal of Pediatric Gastroenterology and Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jpn3.70359","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jpn3.70359","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jpn3.70359","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T03:28:49Z","timestamp":1775446129000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jpn3.70359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,27]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/jpn3.70359"],"URL":"https:\/\/doi.org\/10.1002\/jpn3.70359","archive":["Portico"],"relation":{},"ISSN":["0277-2116","1536-4801"],"issn-type":[{"value":"0277-2116","type":"print"},{"value":"1536-4801","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,27]]}}}