{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T11:10:23Z","timestamp":1778152223967,"version":"3.51.4"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Ultra\u2010short bowel syndrome (USBS) constitutes the most severe form of short bowel syndrome (SBS). Contemporary outcome data are scarce. The aim was to describe the experience of managing children with USBS and assess outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study analyzed children with intestinal failure (IF) managed at a single center between 2018 and 2022. Patients with USBS were matched to SBS controls by age and sex. Demographics and medical history were retrieved. Primary outcomes focused on long\u2010term complications, including cholestasis, central line\u2010associated bloodstream infections (CLABSI), mortality, oral aversion, and vitamin deficiencies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The cohort included 28 children (median age: 44.4 months), 14 with USBS. Compared to SBS, children with USBS had significantly shorter small bowel lengths (percentage of remaining bowel length 6 (4, 8) vs. 25 (18, 29),\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and reduced large bowel percentages (58% vs. 100%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). At data collection, 93% of USBS patients required PN, compared to 30% with SBS. Despite longer PN dependency, rates of cholestasis and CLABSI were similar. Oral aversion was more prevalent in USBS (71% vs. 21%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). High rates of vitamin B12 and iron deficiencies were observed in both groups. No mortality was recorded, and one USBS patient achieved enteral autonomy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>When compared with SBS, children with USBS exhibited greater PN dependency but similar rates of major IF\u2010related complications. These findings highlight that even among children with USBS and intestinal failure, long\u2010term outcomes can be favorable under specialized care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jpn3.70390","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T18:13:28Z","timestamp":1772993608000},"page":"1296-1302","source":"Crossref","is-referenced-by-count":0,"title":["Contemporary challenges and outcomes in children with ultrashort bowel syndrome: A descriptive cohort study"],"prefix":"10.1002","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5177-9478","authenticated-orcid":false,"given":"Hadar","family":"Moran\u2010Lev","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine Cincinnati Ohio USA"},{"name":"Division of Gastroenterology, Hepatology and Nutrition Dana Dwek Children's Hospital Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel A.","family":"Kocoshis","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine Cincinnati Ohio USA"},{"name":"Cincinnati Center of Excellence in Intestinal Rehabilitation (CinCEIR), Cincinnati Children's Hospital Medical Center Cincinnati Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariah","family":"Mukasa","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie B.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine Cincinnati Ohio USA"},{"name":"Cincinnati Center of Excellence in Intestinal Rehabilitation (CinCEIR), Cincinnati Children's Hospital Medical Center Cincinnati Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael A.","family":"Helmrath","sequence":"additional","affiliation":[{"name":"Cincinnati Center of Excellence in Intestinal Rehabilitation (CinCEIR), Cincinnati Children's Hospital Medical Center Cincinnati Ohio"},{"name":"Division of Pediatric Surgery, Department of Surgery Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul W.","family":"Wales","sequence":"additional","affiliation":[{"name":"Cincinnati Center of Excellence in Intestinal Rehabilitation (CinCEIR), Cincinnati Children's Hospital Medical Center Cincinnati Ohio"},{"name":"Division of Pediatric Surgery, Department of Surgery Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine Cincinnati Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8478-6343","authenticated-orcid":false,"given":"Conrad R.","family":"Cole","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine Cincinnati Ohio USA"},{"name":"Cincinnati Center of Excellence in Intestinal Rehabilitation (CinCEIR), Cincinnati Children's Hospital Medical Center Cincinnati Ohio"},{"name":"Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics University of Florida Gainesville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.2232"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2005.10.002"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2016.265"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/133.11.3721"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.09.014"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2001.114481"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2004.02.030"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0000000000000738"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3046.2001.005002080.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001722"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2009.01.031"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000002602"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.1691"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000000586"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/children9101582"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000000239"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000003718"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000003811"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2013.05.062"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000000242"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1597812"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2018.02.004"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intf.2024.100008"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2021.06.025"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.03.062"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.1690"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.2061"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpn3.12276"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000003718"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/0884533617707493"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2022.02.016"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15010062"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1053\/spsu.2001.22384"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2013.07.015"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-020-04764-3"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2023.10.008"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000003736"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000003850"}],"container-title":["Journal 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