{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T06:08:17Z","timestamp":1786946897799,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate neurodevelopment at 24 months in infants surgically treated for esophageal atresia (EA), using the ages and stages questionnaire (ASQ), and identify perinatal and early\u2010life factors associated with developmental delay.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Infants with EA were prospectively enrolled in a structured multidisciplinary follow\u2010up program. Total ASQ scores \u2264185 were considered indicative of significant neurodevelopmental delay, while scores &gt;220 reflected reassuring neurodevelopment. Five skill domains (communication, gross motor skills, fine motor skills, problem solving, and social skills) were also assessed. Clinical, surgical, and growth data were analyzed to identify associated risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 74 infants included, 13 patients (18%) had an ASQ score \u2264185. Lower ASQ scores were significantly associated with prematurity, prolonged hospitalization, multiple surgeries, poor weight gain at 1 and 2 years, and feeding disorders. After adjusting for gestational age and genetic anomalies, prolonged hospitalization remained associated with lower ASQ scores, and higher weight\u2010for\u2010age at 1 and 2 years with better ASQ scores. Communication and social skills were the most severely affected, with approximately 80% of infants in the ASQ\u2009\u2264\u2009185 group scoring below \u20132 standard deviations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although most children with EA demonstrated normal development at 2 years, a minority experienced significant delays, especially in communication and social skills. Early screening and targeted multidisciplinary follow\u2010up are essential to support optimal outcomes in this high\u2010risk population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jpn3.70406","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T10:00:31Z","timestamp":1773914431000},"page":"1386-1393","source":"Crossref","is-referenced-by-count":1,"title":["Neurodevelopmental assessment at 24 months in infants with esophageal atresia: A prospective cohort study"],"prefix":"10.1002","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1691-9212","authenticated-orcid":false,"given":"Julia","family":"Tagmouti","sequence":"first","affiliation":[{"name":"Department of Neonatology and CRMR CRACMO, APHP Necker\u2010Enfants Malades University Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manon","family":"Midavaine","sequence":"additional","affiliation":[{"name":"Department of Neonatology and CRMR CRACMO, APHP Necker\u2010Enfants Malades University Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Sartorius","sequence":"additional","affiliation":[{"name":"Department of Neonatology and CRMR CRACMO, APHP Necker\u2010Enfants Malades University Hospital Paris France"},{"name":"UFR de M\u00e9decine Paris Cit\u00e9 University Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Vinit","sequence":"additional","affiliation":[{"name":"UFR de M\u00e9decine Paris Cit\u00e9 University Paris France"},{"name":"Department of Pediatric Surgery, Urology and Transplantation Necker\u2010Enfants Malades University Hospital, APHP Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elise","family":"Leroy\u2010Terquem","sequence":"additional","affiliation":[{"name":"Department of Neonatology and CRMR CRACMO, APHP Necker\u2010Enfants Malades University Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Beaudoin","sequence":"additional","affiliation":[{"name":"UFR de M\u00e9decine Paris Cit\u00e9 University Paris France"},{"name":"Department of Pediatric Surgery, Urology and Transplantation Necker\u2010Enfants Malades University Hospital, APHP Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsa","family":"Kermorvant\u2010Duchemin","sequence":"additional","affiliation":[{"name":"Department of Neonatology and CRMR CRACMO, APHP Necker\u2010Enfants Malades University Hospital Paris France"},{"name":"UFR de M\u00e9decine Paris Cit\u00e9 University Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Rousseau","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Urology and Transplantation Necker\u2010Enfants Malades University Hospital, APHP Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Lapillonne","sequence":"additional","affiliation":[{"name":"Department of Neonatology and CRMR CRACMO, APHP Necker\u2010Enfants Malades University Hospital Paris France"},{"name":"UFR de M\u00e9decine Paris Cit\u00e9 University Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2015.10.067"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.12943"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2019.05.050"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2021-322158"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2014.12.015"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.12.034"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.17523"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-018-1105-z"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-023-05625-5"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-13-59"},{"key":"e_1_2_8_12_1","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/bjs.18004116544","article-title":"The surgery of infancy and childhood. 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