{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T06:02:55Z","timestamp":1785132175446,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009047","name":"Strategic Research Council","doi-asserted-by":"publisher","award":["346136"],"award-info":[{"award-number":["346136"]}],"id":[{"id":"10.13039\/501100009047","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Our aim was to study the association between residential land cover and greenness during childhood and risk of developing celiac disease (CeD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Celiac Prediction in Sk\u00e5ne study prospectively followed 5969 human leukocyte antigen (HLA)\u2010genotyped children born 2001\u20132004 who were screened for CeD at ages 3, 9, and 15 years in Sk\u00e5ne, Sweden. Among these, 138 (2.3%) children only in the HLA at\u2010risk group were identified and diagnosed with CeD through screening. Children diagnosed with CeD outside the screening program were excluded. For the present study, 2535 children at HLA\u2010risk were included. Residential addresses at birth and screening time points were transformed into spatial coordinates. Coordination of Information on the Environment Land Cover data was collected the corresponding years. Normalized Difference Vegetation Index and Leaf Area Index (LAI) were calculated for the summer months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Higher residential LAI, an indicator of forest and agricultural land cover within a 500\u2010meter buffer, was associated with increased odds of CeD in adjusted logistic regression models at age 3 (OR 1.52, 95% CI: 1.14\u20131.99) and age 9 (OR 1.62, 95% CI: 1.13\u20132.27). After false discovery rate adjustment, several associations with LAI remained statistically significant, whereas no land cover classes were associated with CeD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Residential greenness was associated with increased CeD risk in the Sk\u00e5ne province. This exploratory observational finding warrants replication in independent populations before conclusions can be drawn regarding potential environmental drivers in the etiology of CeD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jpn3.70440","type":"journal-article","created":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T06:12:14Z","timestamp":1776924734000},"page":"127-134","source":"Crossref","is-referenced-by-count":0,"title":["Associations between residential greenness, land cover and risk of celiac disease in genetically at\u2010risk children: Celiac Prediction in Sk\u00e5ne study"],"prefix":"10.1002","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6672-6906","authenticated-orcid":false,"given":"Michaela","family":"Bostr\u00f6m","sequence":"first","affiliation":[{"name":"Department of Clinical Science Lund University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marja 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Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aki","family":"Sinkkonen","sequence":"additional","affiliation":[{"name":"Ecosystems and Environment Research Programme Faculty of Biological and Environmental Sciences University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Agardh","sequence":"additional","affiliation":[{"name":"Department of Clinical Science Lund University Malm\u00f6 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