{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T12:17:06Z","timestamp":1788437826432,"version":"build-2803163510"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Rumination syndrome (RS) is increasingly recognized in pediatrics; however, no tool exists to measure RS severity in children. Thus, the rumination severity index (RumSI) was developed and validated to measure rumination severity in children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We developed a seven\u2010item patient\u2010reported questionnaire, the RumSI, to evaluate RS symptoms and impact on functioning based on clinical experience of pediatric gastroenterologists and psychologists who specialize in caring for children with RS. Patients with RS evaluated at our institution or their parents\/caregivers were asked to complete the RumSI and the Pediatric Quality of Life Inventory (PedsQL) as part of clinical care. An overall RumSI score was calculated and analyzed for correlation with PedsQL. Intrarater and test\u2010retest reliability were assessed in a validation cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 105 children with RS, 66 completed RumSI and PedsQL questionnaires (71% female, median age of 15 years, interquartile range 13\u201317) for a 63% completion rate. RumSI scores ranged from 0 to 26.5 (mean 10.6\u2009\u00b1\u20097.2) out of a total possible 28, with higher scores indicating worse rumination symptoms. RumSI and PedsQL scores were significantly negatively correlated (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u2009\u22120.45,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with every 1\u2010point increase in RumSI score associated with a 1.3\u2010point decrease in PedsQL total score. Test\u2013retest reliability was strong (intraclass correlation coefficient\u2009=\u20090.84).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The newly developed RumSI is the first validated tool designed to measure RS severity in children. RumSI scores negatively correlate well with a widely used pediatric quality of life measure and demonstrate strong test\u2010retest reliability, supporting its use in both clinical care and research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jpn3.70449","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T11:00:43Z","timestamp":1777892443000},"page":"251-257","source":"Crossref","is-referenced-by-count":0,"title":["The rumination severity index: Development and evaluation of a scoring tool for rumination syndrome"],"prefix":"10.1002","volume":"83","author":[{"given":"Janice S.","family":"Khoo","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Nationwide Children's Hospital Division of Gastroenterology, Hepatology, and Nutrition Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Nationwide Children's Hospital Division of Gastroenterology, Hepatology, and Nutrition Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter L.","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Nationwide Children's Hospital Division of Gastroenterology, Hepatology, and Nutrition Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guy","family":"Brock","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics and Center for Biostatistics The Ohio State University Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rejuan","family":"Haque","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics and Center for Biostatistics The Ohio State University Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Sabella","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Nationwide Children's Hospital Division of Gastroenterology, Hepatology, and Nutrition Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neetu Bali","family":"Puri","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Nationwide Children's Hospital Division of Gastroenterology, Hepatology, and Nutrition Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karla","family":"Vaz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Nationwide Children's Hospital Division of Gastroenterology, Hepatology, and Nutrition Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desale","family":"Yacob","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Nationwide Children's Hospital Division of Gastroenterology, Hepatology, and Nutrition Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Di Lorenzo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Nationwide Children's Hospital Division of Gastroenterology, Hepatology, and Nutrition Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2118-7727","authenticated-orcid":false,"given":"Ashley M.","family":"Kroon Van Diest","sequence":"additional","affiliation":[{"name":"Department of Pediatric Psychology and Neuropsychology Nationwide Children's Hospital Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.015"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2017.02.009"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpn3.12449"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.709326"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001395"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000003637"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181fa06f3"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2017.441"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40272-023-00567-w"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000060"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2021.11.008"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230X-12-163"},{"key":"e_1_2_7_14_1","doi-asserted-by":"crossref","unstructured":"VarniJW SeidM KurtinPS.PedsQLTM 4.0: reliability and validity of the Pediatric Quality Of Life InventoryTMversion 4.0 generic core scales in healthy and patient populations.Med Care.2001;39(8):800\u2010812.doi:10.1097\/00005650-200108000-00006","DOI":"10.1097\/00005650-200108000-00006"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-43268-7_41"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpn3.12345"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/dote\/doae009"}],"container-title":["Journal of Pediatric Gastroenterology and 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