{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T12:17:07Z","timestamp":1788437827039,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100010344","name":"Aage og Johanne Louis-Hansens Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010344","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Scotland is known to have the highest incidence of paediatric\u2010onset inflammatory bowel disease (PIBD) in the United Kingdom and one of the highest worldwide; however, data on prevalence is lacking. We aimed to calculate the PIBD incidence and prevalence rates in Scotland during 2015 to 2018.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Incident and prevalent cases of PIBD were prospectively recorded by the three Scottish regional paediatric gastroenterology networks covering all paediatric units nationwide. PIBD was defined as children &lt;16 years of age with Crohn's disease, ulcerative colitis or inflammatory bowel disease type unclassified. The incidence rate for the period from 2015 to 2018, the point prevalence (30th June each year) and the period prevalence (calendar year) were each calculated using publicly accessible Scottish population data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 438 patients were diagnosed with PIBD in Scotland over the 4\u2010year study period, providing an overall incidence rate of 12.0\/100,000 person\u2010years. The number of prevalent patients per year ranged from 518 to 538, with the highest period prevalence 58.5\/100,000 person\u2010years (01 January 2016\u201331 December 2016) and the highest point prevalence 45.9\/100,000 persons (30 June 17). One hundred and fifty\u2010nine patients \u226516 years of age remained within paediatric services in 2017; differences in transition practices were observed across regions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The Scottish PIBD incidence and prevalence remain the highest reported in nationwide studies worldwide (aged\u2009&lt;\u200916 years). The high prevalence is in keeping with the high incidence rate and minimal mortality rate, so continues to rise. The true caseload within paediatric services, including patients \u226516 years of age, may be up to 30% higher.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jpn3.70450","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T08:39:56Z","timestamp":1777538396000},"page":"285-290","source":"Crossref","is-referenced-by-count":0,"title":["The incidence and prevalence of paediatric inflammatory bowel disease in Scotland: A nationwide study from 2015 to 2018"],"prefix":"10.1002","volume":"83","author":[{"given":"Christopher J.","family":"Burgess","sequence":"first","affiliation":[{"name":"Child Life and Health, Centre for Inflammation Research University of Edinburgh Edinburgh UK"},{"name":"Department of Paediatric Gastroenterology and Nutrition Royal Hospital for Children and Young People Edinburgh UK"},{"name":"Department of Gastroenterology, Hepatology and Liver Transplant Queensland Children's Hospital Brisbane Queensland Australia"},{"name":"Faculty of Medicine University of Queensland Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6956-7676","authenticated-orcid":false,"given":"Mikkel","family":"Malham","sequence":"additional","affiliation":[{"name":"Child Life and Health, Centre for Inflammation Research University of Edinburgh Edinburgh UK"},{"name":"Department of Paediatric Gastroenterology and Nutrition Royal Hospital for Children and Young People Edinburgh UK"},{"name":"Department of Paediatric and Adolescent Medicine Copenhagen University Hospital \u2013 Amager and Hvidovre Hvidovre Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iain","family":"Chalmers","sequence":"additional","affiliation":[{"name":"Department of Paediatric Gastroenterology Royal Aberdeen Children's Hospital Aberdeen UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel E.","family":"Harris","sequence":"additional","affiliation":[{"name":"Department of Paediatric Gastroenterology and Nutrition Royal Hospital for Children Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Hansen","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine and Gastroenterology, School of Medicine University of Dundee Dundee UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard K.","family":"Russell","sequence":"additional","affiliation":[{"name":"Child Life and Health, Centre for Inflammation Research University of Edinburgh Edinburgh UK"},{"name":"Department of Paediatric Gastroenterology and Nutrition Royal Hospital for Children and Young People Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Henderson","sequence":"additional","affiliation":[{"name":"Child Life and Health, Centre for Inflammation Research University of Edinburgh Edinburgh UK"},{"name":"Department of Paediatric Gastroenterology and Nutrition Royal Hospital for Children and Young People Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Wilson","sequence":"additional","affiliation":[{"name":"Child Life and Health, Centre for Inflammation Research University of Edinburgh Edinburgh UK"},{"name":"Department of Paediatric Gastroenterology and Nutrition Royal Hospital for Children and Young People Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.06.081"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjad144"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ygh2.368"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2017.228"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000002842"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjac138"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2021.12.282"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-020-00360-x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-025-08940-0"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.30.5.618"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200112000-00007"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21797"},{"key":"e_1_2_9_14_1","unstructured":"Anon.Mid\u2010Year 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