{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T10:54:24Z","timestamp":1791975264513,"version":"4.4.0"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. pediatr. gastroenterol. nutr."],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Dietary factors may impact asthma indirectly by modulating the composition and activity of the gut microbiota. This study aimed to explore the potential relationship between gut microbiota\u2010friendly diet and both the prevalence and severity of asthma in children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We selected a total of 2256 children from the 2021\u20132023 National Health and Nutrition Examination Survey. The gut microbiota\u2010friendly diet was assessed using the Diet\u2010Gut Microbiome Index (DI\u2010GM), which incorporates 14 specific food constituents. To calculate the DI\u2010GM, two non\u2010consecutive 24\u2010h dietary recalls data were used, from which the relevant food constituents were derived. A higher DI\u2010GM score indicates greater alignment with a gut microbiota\u2010friendly diet.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 2256 U.S. children, the weighted prevalence of asthma is 13.36%. In fully adjusted models, DI\u2010GM was not significantly associated with asthma prevalence overall or within any subgroups. However, higher DI\u2010GM (T2) was significantly associated with a lower risk of the mild asthma phenotype in the 5\u201316 age group. In contrast, no significant associations were observed between DI\u2010GM and asthma severity in the other age groups. Subgroup analysis showed a higher DI\u2010GM score was significantly correlated with a lower risk for asthma in subgroups stratified by obesity status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Higher DI\u2010GM scores were significantly inversely associated with asthma severity risk in children aged 5\u201316 years and in obese individuals. These cross\u2010sectional findings support the need for longitudinal studies to determine whether dietary modulation may affect asthma severity via microbiota\u2010dependent mechanisms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jpn3.70605","type":"journal-article","created":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T10:42:48Z","timestamp":1791974568000},"source":"Crossref","is-referenced-by-count":0,"title":["The relationship between gut microbiota\u2010friendly diet and the prevalence and severity of asthma in children"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8970-0884","authenticated-orcid":false,"given":"Li\u2010Juan","family":"Tan","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, Shanghai Children's Hospital School of Medicine, Shanghai Jiao Tong University Shanghai China"},{"name":"Institute of Pediatric Infection, Immunity, and Critical Care Medicine, Shanghai Children's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China"},{"name":"Department of Food and Nutrition Chung\u2010Ang University Anseong\u2010Si South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xifeng","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Shanghai Children's Hospital School of Medicine, Shanghai Jiao Tong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijun","family":"Shan","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Shanghai Children's Hospital School of Medicine, Shanghai Jiao Tong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqian","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Shanghai Children's Hospital School of Medicine, Shanghai Jiao Tong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Shanghai Children's Hospital School of Medicine, Shanghai Jiao Tong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiping","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Shanghai Children's Hospital School of Medicine, Shanghai Jiao Tong University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6691-6834","authenticated-orcid":false,"given":"Jialei","family":"Fu","sequence":"additional","affiliation":[{"name":"Vanke School of Public Health Tsinghua University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yucai","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Shanghai Children's Hospital School of Medicine, Shanghai Jiao Tong University Shanghai China"},{"name":"Institute of Pediatric Infection, Immunity, and Critical Care Medicine, Shanghai Children's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3649-5274","authenticated-orcid":false,"given":"Yun","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Shanghai Children's Hospital School of Medicine, Shanghai Jiao Tong University Shanghai China"},{"name":"Institute of Pediatric Infection, Immunity, and Critical Care Medicine, Shanghai Children's Hospital Shanghai Jiao Tong University School of Medicine Shanghai 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