{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T10:59:35Z","timestamp":1771671575200,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,7,20]],"date-time":"2024-07-20T00:00:00Z","timestamp":1721433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPGN rep."],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a case of moderately severe acute pancreatitis, hyperglycemia, acidosis, splenic, superior mesenteric, and portal vein thrombosis in relation to multisystem inflammatory syndrome in children (MIS\u2010C). The patient responded well to intravenous immune globulin, corticosteroids, antibiotics, systemic anticoagulation, and drainage of peripancreatic fluid. The case highlights the polymorphic presentation of MIS\u2010C and advises high level of suspicion for unusual, severe cases unresponsive to routine care.<\/jats:p>","DOI":"10.1002\/jpr3.12113","type":"journal-article","created":{"date-parts":[[2024,7,20]],"date-time":"2024-07-20T11:30:13Z","timestamp":1721475013000},"page":"567-571","source":"Crossref","is-referenced-by-count":2,"title":["Multisystem inflammatory syndrome in children presenting as acute severe necrotizing pancreatitis: A case report"],"prefix":"10.1002","volume":"5","author":[{"given":"Hanna","family":"Distel","sequence":"first","affiliation":[{"name":"Department of Pediatrics, John A Burns School of Medicine University of Hawai'i Honolulu Hawaii USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelley","family":"Hutchins","sequence":"additional","affiliation":[{"name":"Division of Hematology Oncology University of Hawai'I Honolulu Hawaii USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prashant J.","family":"Purohit","sequence":"additional","affiliation":[{"name":"Division of Critical Care Medicine University of Hawai'I Honolulu Hawaii USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8806-8987","authenticated-orcid":false,"given":"Rodolfo E.","family":"B\u00e9gu\u00e9","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases University of Hawai'I Honolulu Hawaii USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,20]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"CDC Health Alert Network (00432).Multisystem Inflammatory Syndrome in Children (MIS\u2010C) Associated with Coronavirus Disease 2019 (COVID\u201019);2020.https:\/\/emergency.cdc.gov\/han\/2020\/han00432.asp"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.rr7104a1"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7310a2"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31094-1"},{"key":"e_1_2_7_6_1","unstructured":"SARS\u2010CoV\u20102 IgG (Product 6R86).Abbott Laboratories (Abbott Park IL USA);2022. Accessed March 14 2024.https:\/\/www.fda.gov\/media\/137383\/download\/"},{"key":"e_1_2_7_7_1","unstructured":"Elecsys Anti SARS\u2010CoV\u20102 S (Reference 09289267190).Roche Diagnostics;2023. Accessed March 14 2024.https:\/\/fda.gov\/media\/144037\/download\/"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000002935"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e31824f1516"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2020.12.005"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000002860"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/ipcares.ipcares_182_21"},{"key":"e_1_2_7_13_1","first-page":"253","article-title":"Acute pancreatitis in children with COVID\u201019 associated multisystem inflammatory syndrome","volume":"96","author":"Zubiaurre MT","year":"2022","journal-title":"Anales de Pediatria"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021680"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/PG9.0000000000000150"},{"issue":"4","key":"e_1_2_7_16_1","article-title":"Liver and pancreatic involvement in children with multisystem inflammatory syndrome related to SARS\u2010CoV\u20102: a monocentric study","volume":"9","author":"Giannattasio A","year":"2022","journal-title":"Children (Basel)"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001583"},{"issue":"1","key":"e_1_2_7_18_1","first-page":"25","article-title":"Acute pancreatitis as a manifestation of multisystem inflammatory syndrome among children (MIS\u2010C): a rare case","volume":"10","author":"Srividya KV","year":"2024","journal-title":"IP Intern J Med Paedtr Oncol"},{"issue":"2","key":"e_1_2_7_19_1","first-page":"60","article-title":"COVID\u201019 associated multisystem inflammatory syndrome in children presenting as acute necrotizing pancreatitis with walled\u2010off pancreatic necrosis","volume":"5","author":"Vijay P","year":"2023","journal-title":"Pediatr Infect Dis"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-020-00826-9"}],"container-title":["JPGN Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jpr3.12113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T12:29:02Z","timestamp":1732710542000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jpr3.12113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,20]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1002\/jpr3.12113"],"URL":"https:\/\/doi.org\/10.1002\/jpr3.12113","archive":["Portico"],"relation":{},"ISSN":["2691-171X","2691-171X"],"issn-type":[{"value":"2691-171X","type":"print"},{"value":"2691-171X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,20]]}}}