{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T17:01:21Z","timestamp":1762102881134,"version":"3.37.3"},"reference-count":5,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T00:00:00Z","timestamp":1724630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JPGN rep."],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Inflammatory bowel disease (IBD) is a chronic condition, characterized by recurrent inflammation of the gastrointestinal tract. While the primary focus of IBD management consists in controlling gastrointestinal symptoms, IBD also presents an increased risk of thromboembolic complications. Tumor necrosis factor alpha (TNF\u2010\u03b1) inhibitors, namely infliximab, have become increasingly common in the management of multiple chronic inflammatory diseases such as IBD. However, recent studies have shown an association between treatment with infliximab and an increased thrombotic risk. We report an unusual case of retinal vein thrombosis in a patient with ulcerative colitis (UC) that occurred during infliximab infusion. This case highlights the need to remain vigilant when administering infliximab to individuals with IBD, particularly those with additional risk factors for thrombosis.<\/jats:p>","DOI":"10.1002\/jpr3.12122","type":"journal-article","created":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T09:53:29Z","timestamp":1724666009000},"page":"523-524","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Central retinal vein occlusion after infliximab therapy in a young patient with ulcerative colitis"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4574-7119","authenticated-orcid":false,"given":"Joana Victor","family":"Lage","sequence":"first","affiliation":[{"name":"Department of Pediatric Gastroenterology Centro Hospitalar Universit\u00e1rio S\u00e3o Jo\u00e3o Porto Portugal"},{"name":"Department of Pediatrics Hospital Professor Doutor Fernando Fonseca Amadora Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana Filipe","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Centro Hospitalar Universit\u00e1rio S\u00e3o Jo\u00e3o Porto Portugal"},{"name":"Department of Pediatrics Hospital Sousa Martins, Unidade Local de Sa\u00fade da Guarda Guarda Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margarida","family":"Vicente\u2010Ferreira","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Centro Hospitalar Universit\u00e1rio S\u00e3o Jo\u00e3o Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana Rodrigues","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Centro Hospitalar Universit\u00e1rio S\u00e3o Jo\u00e3o Porto Portugal"},{"name":"Department of Ophthalmology Centro Hospitalar Universit\u00e1rio S\u00e3o Jo\u00e3o Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Pais","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Centro Hospitalar Universit\u00e1rio S\u00e3o Jo\u00e3o Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9u","family":"Espinheira","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Centro Hospitalar Universit\u00e1rio S\u00e3o Jo\u00e3o Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eunice","family":"Trindade","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Centro Hospitalar Universit\u00e1rio S\u00e3o Jo\u00e3o Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/neurolint13010011"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07368.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cxo.12904"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e3282f376ac"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-27492011000300015"}],"container-title":["JPGN Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jpr3.12122","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T12:29:54Z","timestamp":1732710594000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jpr3.12122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,26]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1002\/jpr3.12122"],"URL":"https:\/\/doi.org\/10.1002\/jpr3.12122","archive":["Portico"],"relation":{},"ISSN":["2691-171X","2691-171X"],"issn-type":[{"type":"print","value":"2691-171X"},{"type":"electronic","value":"2691-171X"}],"subject":[],"published":{"date-parts":[[2024,8,26]]},"assertion":[{"value":"2024-06-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}