{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T04:01:36Z","timestamp":1747368096609,"version":"3.40.5"},"reference-count":8,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T00:00:00Z","timestamp":1736726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JPGN rep."],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report the case of a 19\u2010year\u2010old White male diagnosed with familial adenomatous polyposis (FAP), Gardner's syndrome (GS) phenotype, status post total colectomy, who developed progressive dysphagia and weight loss. He was diagnosed with achalasia based on imaging and esophageal manometry. The patient underwent a Heller myotomy with the resolution of symptoms. To date, no previous literature has reported on concurrent FAP or GS and achalasia. Although FAP and achalasia are both rare conditions with no previously known concurrent occurrence, association, or described syndrome, it is important to be vigilant of this new case report finding. One must also consider the increased risk of malignancy in patients with achalasia in addition to the significant risk of malignancy in patients with FAP\/GS.<\/jats:p>","DOI":"10.1002\/jpr3.12161","type":"journal-article","created":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T06:51:53Z","timestamp":1736837513000},"page":"166-169","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Familial polyposis syndrome and achalasia in a young adult"],"prefix":"10.1002","volume":"6","author":[{"given":"Gabriella A.","family":"Lorusso Vivas","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Miller School of Medicine University of Miami Miami Florida USA"},{"name":"Division of Neonatology, Department of Pediatrics, LAC+USC Medical Center, Keck School of Medicine University of Southern California Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann\u2010Christina","family":"Brady","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, DeWitt\u2010Daughtry Department of Surgery, Miller School of Medicine University of Miami Miami Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8882-2900","authenticated-orcid":false,"given":"Alejandro","family":"Llanos\u2010Chea","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Miller School of Medicine University of Miami Miami Florida USA"},{"name":"Division of Pediatric Gastroenterology, Hepatology &amp; Nutrition University of Texas Southwestern Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2014.229"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2018-0570-RA"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1067\/j.cpsurg.2019.01.001"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12477"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13053-017-0065-x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.7869\/tg.259"},{"issue":"5","key":"e_1_2_6_8_1","first-page":"249","article-title":"Tailoring therapy for achalasia","volume":"16","author":"Richter JE","year":"2020","journal-title":"Gastroenterol Hepatol (N Y)"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jgh3.12132"}],"container-title":["JPGN Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jpr3.12161","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T03:56:37Z","timestamp":1747281397000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jpr3.12161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,13]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1002\/jpr3.12161"],"URL":"https:\/\/doi.org\/10.1002\/jpr3.12161","archive":["Portico"],"relation":{},"ISSN":["2691-171X","2691-171X"],"issn-type":[{"type":"print","value":"2691-171X"},{"type":"electronic","value":"2691-171X"}],"subject":[],"published":{"date-parts":[[2025,1,13]]},"assertion":[{"value":"2024-06-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}