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We present a pediatric case of a pancreatic head solid pseudopapillary neoplasm (SPN) presenting with duodenal ulceration and recurrent upper GI bleeding. This case highlights pancreatic SPNs as a rare extrinsic cause of duodenal ulceration. Recurrence and progression in size and extent of a duodenal ulceration in the absence of other inciting factors should raise suspicion for an extraluminal etiology.<\/jats:p>","DOI":"10.1002\/jpr3.70003","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T13:47:56Z","timestamp":1741700876000},"page":"189-192","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["SPNing our wheels\u2014Pancreatic solid pseudopapillary neoplasm as an extraluminal etiology of persistent duodenal ulceration"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8489-8425","authenticated-orcid":false,"given":"Kanak V.","family":"Kennedy","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"},{"name":"Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics Stanford University School of Medicine Palo Alto California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jibraan A.","family":"Fawad","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y. Dana","family":"Neugut","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doris","family":"Valenzuela\u2010Araujo","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Coe","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tricia R.","family":"Bhatti","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine 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