{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T12:11:48Z","timestamp":1778155908855,"version":"3.51.4"},"reference-count":8,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:00:00Z","timestamp":1773792000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:00:00Z","timestamp":1773792000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JPGN rep."],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Gastric signet\u2010ring cell carcinoma (SRCC) is a rare form of gastric cancer characterized by mucus\u2010rich tumor cells forming a distinctive ring\u2010like appearance and is exceedingly rare in children, accounting for less than 1% of all childhood malignancies. We report a case of a 14\u2010year\u2010old patient who presented with melena, hematemesis, and syncope. Upper gastrointestinal endoscopy revealed an ulcerative mass located in the gastric cardia. Histopathological examination confirmed gastric adenocarcinoma demonstrating signet\u2010ring cell features. The patient underwent laparoscopic\u2010assisted radical proximal gastrectomy, esophagogastric anastomosis, abdominal drainage, and a D2 lymphadenectomy, which includes dissection of both perigastric and second\u2010tier lymph nodes. The final diagnosis was SRCC of the stomach. Postoperative Tumor Node Metastasis (TNM) staging was stage III (T3N0M0). Follow\u2010up indicates that the patient remains in good health and has remained symptom\u2010free for 5 years. Given the rarity of this malignancy and the limited number of pediatric case studies, there is an urgent need to accumulate additional clinical and immunohistochemical data to enhance understanding and improve diagnostic accuracy.<\/jats:p>","DOI":"10.1002\/jpr3.70084","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T10:11:06Z","timestamp":1773828666000},"page":"285-288","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Gastric signet\u2010ring cell carcinoma in a child: A clinical case study"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6849-3587","authenticated-orcid":false,"given":"Jiaxian","family":"Wang","sequence":"first","affiliation":[{"name":"Zhuhai Campus of Zunyi Medical University Zhuhai 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Zhuhai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao Hui","family":"He","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Zhuhai Hospital The Fifth Affiliated Hospital of Zunyi Medical University Zhuhai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ning","family":"Liu","sequence":"additional","affiliation":[{"name":"Rehabilitation Therapy Teaching and Research Division, Zhuhai Campus Zunyi Medical University Zhuhai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i21.3446"},{"key":"e_1_2_8_3_1","first-page":"283","volume-title":"National Healthy Commission of the People's Republic of China. 2019 China Health Statistics 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