{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T18:51:37Z","timestamp":1768589497104,"version":"3.49.0"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:00:00Z","timestamp":1759017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JPGN rep."],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Senna (sennosides) is a natural stimulant laxative containing anthraquinone glycosides, commonly used to treat constipation. We present the case of a healthy 2\u2010year\u2010old female (~12.5\u2009kg) who is not yet toilet\u2010trained and accidentally ingested a single 15\u2009mg chocolate\u2010flavored sennoside chew (1.2\u2009mg\/kg). This led to sharply demarcated erythema, pain, and blisters in her diaper area. In the emergency department, the blisters were treated by unroofing, topical mupirocin application, a petrolatum dressing, and a 5\u2010day course of oral cephalexin. The burn injury healed without complications at a follow\u2010up visit. This case highlights the risk of senna\u2010induced burns in diapered toddlers, as prolonged stool\u2010skin contact can cause blistering that mimics abusive injury. Inquiries about sennoside use should be made when perineal burns are observed in pre\u2010continent children to prevent misdiagnosis of child abuse. Preventive measures, including caregiver education, child\u2010resistant packaging, and safe medication storage, are essential.<\/jats:p>","DOI":"10.1002\/jpr3.70087","type":"journal-article","created":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T10:24:45Z","timestamp":1759055085000},"page":"434-436","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Laxative\u2010induced contact burns from accidental ingestion of senna in a 2\u2010year\u2010old female"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3688-7286","authenticated-orcid":false,"given":"Tolulope","family":"Olorunsogo","sequence":"first","affiliation":[{"name":"Pediatric Gastroenterology, Hepatology and Nutrition University of Nebraska Medical Center, Children's Nebraska Omaha Nebraska USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian O.","family":"Oarhe","sequence":"additional","affiliation":[{"name":"Pediatric Emergency University of Nebraska Medical Center, Children's Nebraska Omaha Nebraska USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad R.","family":"Miri","sequence":"additional","affiliation":[{"name":"Pediatric Gastroenterology, Hepatology and Nutrition University of Nebraska Medical Center, Children's Nebraska Omaha Nebraska USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000001222"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1C439"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.107.1.178"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13068"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-021-01071-y"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-85852-6.00021-4"},{"key":"e_1_2_8_8_1","first-page":"1349","article-title":"Senna induced blistering diaper dermatitis","volume":"2","author":"Schweitz G","year":"2017","journal-title":"Ann Clin Case Rep"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2006.00266.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2018.01.002"},{"key":"e_1_2_8_11_1","unstructured":"Uptodate Lexidrug. Pediatric & Neonatal Dosage Handbook. Wolters Kluwer Health; 2025.https:\/\/online.lexi.com\/lco\/action\/doc\/retrieve\/docid\/pdh_f\/129753?searchUrl=%2Flco%2Faction%2Fsearch%3Fq%3D6943%26nq%3Dtrue%26t%3Dglobalid%26origin%3Dapi#dop."}],"container-title":["JPGN Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jpr3.70087","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T04:01:58Z","timestamp":1763006518000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jpr3.70087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,28]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/jpr3.70087"],"URL":"https:\/\/doi.org\/10.1002\/jpr3.70087","archive":["Portico"],"relation":{},"ISSN":["2691-171X","2691-171X"],"issn-type":[{"value":"2691-171X","type":"print"},{"value":"2691-171X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,28]]},"assertion":[{"value":"2025-04-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}