{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T15:56:58Z","timestamp":1786636618767,"version":"build-2736575974"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JPGN rep."],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Infantile hepatic hemangioma (IHH) can cause severe complications such as high\u2010output cardiac failure and growth faltering, requiring prompt diagnosis and intervention. In the absence of standardized treatment guidelines, propranolol has emerged as an effective and well\u2010tolerated therapy. We report a female infant with multifocal IHH who presented with high\u2010output cardiac failure, hepatomegaly, and growth faltering. She experienced rapid and sustained clinical as well as radiologic improvement with propranolol therapy. This case reinforces propranolol's role as a safe, effective first\u2010line therapy for symptomatic IHH and underscores the importance of early multidisciplinary care.<\/jats:p>","DOI":"10.1002\/jpr3.70180","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T04:53:11Z","timestamp":1775796791000},"page":"387-390","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Successful propranolol therapy for infantile hepatic hemangioma with cardiac failure"],"prefix":"10.1002","volume":"7","author":[{"given":"Fadhel Al","family":"Ateeqi","sequence":"first","affiliation":[{"name":"Department of Pediatrics Danat Al Emarat Hospital for Women and Children  Abu Dhabi United\u00a0Arab\u00a0Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ala K.","family":"Shaikhkhalil","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology Hepatology, and Nutrition, Sheikh Khalifa Medical City  Abu Dhabi United\u00a0Arab\u00a0Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitham","family":"Talo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Danat Al Emarat hospital for Women and Children  Abu Dhabi United\u00a0Arab\u00a0Emirates"},{"name":"Department of Pediatrics Mohammed Bin Rashid University Dubai United\u00a0Arab\u00a0Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naeem","family":"Jagirdar","sequence":"additional","affiliation":[{"name":"Healthpoint Hospital Abu Dhabi United\u00a0Arab\u00a0Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0376-7186","authenticated-orcid":false,"given":"Mahdia","family":"AL\u2010Haidar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Sheikh Khalifa Medical City Abu Dhabi United\u00a0Arab\u00a0Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.5223\/pghn.2020.23.1.72"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/pcmedi\/pbac006"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3182201a4e"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.963"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000014078"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2024.1336742"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000020728"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.54847\/cp.2022.02.20"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000012863"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-019-1200-6"}],"container-title":["JPGN Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jpr3.70180","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jpr3.70180","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jpr3.70180","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T14:59:03Z","timestamp":1786633143000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jpr3.70180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,9]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/jpr3.70180"],"URL":"https:\/\/doi.org\/10.1002\/jpr3.70180","archive":["Portico"],"relation":{},"ISSN":["2691-171X","2691-171X"],"issn-type":[{"value":"2691-171X","type":"print"},{"value":"2691-171X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,9]]},"assertion":[{"value":"2025-12-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}