{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T09:49:29Z","timestamp":1792057769761,"version":"4.4.0"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JPGN rep."],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Achalasia is a rare esophageal motility disorder in children, often leading to delayed diagnosis. We report the first two pediatric cases treated with peroral endoscopic myotomy (POEM) at our center, both classified as type II achalasia and complicated by mucosal disease. A 15\u2010year\u2010old girl presented with progressive dysphagia and weight loss, diagnosed with type II achalasia and Candida esophagitis. A 13\u2010year\u2010old boy exhibited similar symptoms with a 27\u2010kg weight loss; histology revealed concurrent eosinophilic esophagitis. Both underwent successful POEM. These cases illustrate the clinical heterogeneity of pediatric achalasia and emphasize the importance of recognizing concomitant mucosal conditions that may delay diagnosis. POEM appears to be a safe and effective, minimally invasive treatment in the pediatric population, even in complex scenarios.<\/jats:p>","DOI":"10.1002\/jpr3.70260","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T09:29:53Z","timestamp":1792056593000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Two pediatric type II achalasia cases complicated by candidal and eosinophilic esophagitis: Successful peroral endoscopic myotomy treatment"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6459-9147","authenticated-orcid":false,"given":"Fabio","family":"Rotondo","sequence":"first","affiliation":[{"name":"Department of Pediatrics Fondazione IRCCS \u201cCasa Sollievo della Sofferenza\u201d San Giovanni Rotondo Italy"},{"name":"Department of Pediatrics University of Foggia Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Marseglia","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Fondazione IRCCS \u201cCasa Sollievo della Sofferenza\u201d San Giovanni Rotondo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Locatelli","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Fondazione IRCCS \u201cCasa Sollievo della Sofferenza\u201d San Giovanni Rotondo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalila","family":"Tedeschi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Foggia Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Gentile","sequence":"additional","affiliation":[{"name":"Departmend of Gastroenterology Fondazione IRCCS \u201cCasa Sollievo della Sofferenza\u201d San Giovanni Rotondo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Perri","sequence":"additional","affiliation":[{"name":"Departmend of Gastroenterology Fondazione IRCCS \u201cCasa Sollievo della Sofferenza\u201d San Giovanni Rotondo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Rosa","family":"Pastore","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Fondazione IRCCS \u201cCasa Sollievo della Sofferenza\u201d San Giovanni Rotondo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo Pettoello","family":"Mantovani","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Foggia Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"issue":"12","key":"e_1_2_9_2_1","first-page":"209","article-title":"Achalasia\u2014a disease of unknown cause that is often 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