{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T23:40:29Z","timestamp":1764027629915},"reference-count":10,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2003,10,1]],"date-time":"2003-10-01T00:00:00Z","timestamp":1064966400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[2003,10]]},"DOI":"10.1002\/jps.10464","type":"journal-article","created":{"date-parts":[[2003,9,17]],"date-time":"2003-09-17T10:18:29Z","timestamp":1063793909000},"page":"1981-1989","source":"Crossref","is-referenced-by-count":5,"title":["Chemical Reactivity of Ro-26-9228, 1\u03b1-Fluoro-25-hydroxy-16,23E-diene-26,27-bishomo-20-epi-cholecalciferol in Aqueous Solution"],"prefix":"10.1016","volume":"92","author":[{"given":"Michael","family":"Brandl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanzhou","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Pease","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marites","family":"Holper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elvira","family":"Hooijmaaijer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yvonne","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1002\/jps.10464_bb0010","doi-asserted-by":"crossref","first-page":"9836","DOI":"10.1021\/ja00051a016","article-title":"New strategies for the synthesis of vitamin D metabolites via palladium\u2010catalyzed reactions","volume":"114","author":"Trost","year":"1992","journal-title":"J Am Chem Soc"},{"issue":"23","key":"10.1002\/jps.10464_bb0015","doi-asserted-by":"crossref","first-page":"4662","DOI":"10.1021\/jm9802618","article-title":"New 1alpha,25\u2010dihydroxy\u201019\u2010norvitamin D3 compounds of high biological activity: Synthesis and biological evaluation of 2\u2010hydroxymethyl, 2\u2010methyl, and 2\u2010methylene analogues","volume":"41","author":"Sicinski","year":"1998","journal-title":"J Med Chem"},{"issue":"11","key":"10.1002\/jps.10464_bb0020","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1016\/S0968-0896(98)00164-3","article-title":"Total synthesis of 25\u2010hydroxy\u201016,23E\u2010diene vitamin D3 and 1 alpha,25\u2010dihydroxy\u201016,23E\u2010diene vitamin D3: Separation of genomic and nongenomic vitamin D activities","volume":"6","author":"Kabat","year":"1998","journal-title":"Bioorg Med Chem"},{"issue":"5 Suppl 5","key":"10.1002\/jps.10464_bb0025","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1053\/ajkd.2001.28111","article-title":"Therapeutic uses of vitamin D analogues","volume":"38","author":"Brown","year":"2001","journal-title":"Am J Kidney Dis"},{"key":"10.1002\/jps.10464_bb0030","unstructured":"Nestor JJ Jr,Manchand PS,Uskokovic MR,Vickery BH.1999. Preparation of fluorinated vitamin D3 analogs. U.S. Patent 97\u2010857569 970516."},{"key":"10.1002\/jps.10464_bb0035","unstructured":"Batcho AD,Bryce GF,Hennessy BM,Iacobelli JA,Uskokovic MR.1997. Preparation of fluorinated vitamin D3 analogs for the treatment of osteoporosis. European Patent Application 808833."},{"issue":"5","key":"10.1002\/jps.10464_bb0040","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1210\/endo.143.5.8777","article-title":"Cellular and molecular events associated with the bone\u2010protecting activity of the noncalcemic vitamin D analog Ro\u201026\u20109228 in osteopenic rats","volume":"145","author":"Peleg","year":"2002","journal-title":"Endocrinology"},{"key":"10.1002\/jps.10464_bb0045","series-title":"Medical economics","first-page":"2141","year":"1996"},{"key":"10.1002\/jps.10464_bb0050","series-title":"100 and more basic NMR experiments","author":"Braun","year":"1996"},{"issue":"1\u20136","key":"10.1002\/jps.10464_bb0055","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/0960-0760(95)00107-B","article-title":"Chemistry and conformation of vitamin D molecules","volume":"53","author":"Okamura","year":"1995","journal-title":"J Steroid Biochem Mol Biol"}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354916313259?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354916313259?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,23]],"date-time":"2019-02-23T19:57:41Z","timestamp":1550951861000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022354916313259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,10]]},"references-count":10,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2003,10]]}},"alternative-id":["S0022354916313259"],"URL":"https:\/\/doi.org\/10.1002\/jps.10464","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[2003,10]]}}}