{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:39:52Z","timestamp":1791193192657,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1002\/jps.23271","type":"journal-article","created":{"date-parts":[[2012,7,23]],"date-time":"2012-07-23T21:33:17Z","timestamp":1343079197000},"page":"3799-3810","source":"Crossref","is-referenced-by-count":9,"title":["Calorimetric, FTIR and 1H NMR measurements in combination with DFT calculations for monitoring solid\u2010state changes of dynamics of sibutramine hydrochloride"],"prefix":"10.1016","volume":"101","author":[{"given":"Aleksandra","family":"Pajzderska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorota M.","family":"Chudoba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jadwiga","family":"Mielcarek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"W\u0105sicki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1002\/jps.23271_bb0010","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1111\/j.1365-2710.2010.01217.x","article-title":"Variation of inflammatory parameters after sibutramine treatment compared to placebo in type 2 diabetic patients","volume":"36","author":"Derosa","year":"2011","journal-title":"J Clin Pharm Ther"},{"key":"10.1002\/jps.23271_bb0015","first-page":"616","article-title":"A case of sibutramine\u2010induced hyperprolactinemia","volume":"32","author":"Leaes","year":"2011","journal-title":"Neuro Endocrinol Lett"},{"key":"10.1002\/jps.23271_bb0020","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.2165\/00003495-199856060-00019","article-title":"Sibutramine: A review of its contribution to the management of obesity","volume":"56","author":"McNeely","year":"1998","journal-title":"Drugs"},{"key":"10.1002\/jps.23271_bb0025","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.2165\/00003495-200565100-00006","article-title":"Pharmacotherapy for obesity","volume":"65","author":"Ioannides\u2010Demos","year":"2005","journal-title":"Drugs"},{"key":"10.1002\/jps.23271_bb0030","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1177\/0091270010388651","article-title":"Effects of clopidogrel on the pharmacokinetics of sibutramine and its active metabolites","volume":"51","author":"Bae","year":"2011","journal-title":"J Clin Pharmacol"},{"key":"10.1002\/jps.23271_bb0035","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1517\/14712598.2011.619974","article-title":"Novel strategy for the use of leptin for obesity therapy","volume":"11","author":"Tam","year":"2011","journal-title":"Expert Opin Biol Ther"},{"key":"10.1002\/jps.23271_bb0040","unstructured":"Kang TW, Jeon KF, Shon HJ, Choi WK, Chang KY, Jin KY, Lee KS. 2006. Anhydrous sibutramine malates and preparation method thereof. Patent WO2006090999."},{"key":"10.1002\/jps.23271_bb0045","doi-asserted-by":"crossref","first-page":"5229","DOI":"10.1002\/jps.21387","article-title":"Crystal chemistry of sibutramine: Thermal, diffractometric and spectroscopic characterization","volume":"97","author":"Maccaroni","year":"2008","journal-title":"J Pharm Sci"},{"key":"10.1002\/jps.23271_bb0050","first-page":"513","article-title":"Crystal structure of N\u2010(1\u2010(1\u2010(p\u2010chlorophenyl)cyclobutyl)\u20103\u2010methylbutyl)\u2010N,N\u2010dimethylamine hydrochloride monohydrate (C17H27NCl)Cl_H2O","volume":"220","author":"Chen","year":"2005","journal-title":"Z Kristallogr"},{"key":"10.1002\/jps.23271_bb0055","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1002\/jps.20870","article-title":"A solid\u2010state chemist's view of the crystal polymorphism of organic compounds","volume":"96","author":"Gavezzotti","year":"2007","journal-title":"J Pharm Sci"},{"key":"10.1002\/jps.23271_bb0060","series-title":"Molecular crystals and molecules","author":"Kitajgorodski","year":"1973"},{"key":"10.1002\/jps.23271_bb0065","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.cpc.2004.06.071","article-title":"Computer calculation of the Van Vleck second moment for materials with internal rotation of spin groups","volume":"162","author":"Goc","year":"2004","journal-title":"Comput Phys Commun"},{"key":"10.1002\/jps.23271_bb0070","series-title":"Gaussian 2009","author":"Frisch","year":"2009"},{"key":"10.1002\/jps.23271_bb0075","series-title":"Computational chemistry: A practical guide for applying techniques to real world problems (electronic)","author":"Young","year":"2001"},{"key":"10.1002\/jps.23271_bb0080","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s10973-009-0200-7","article-title":"Sibutramine hydrochloride monohydrate\u2014Thermal behavior, decomposition kinetics and compatibility studies","volume":"100","author":"Oliveira","year":"2010","journal-title":"J Therm Anal Calorim"},{"key":"10.1002\/jps.23271_bb0085","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.1039\/p19960002583","article-title":"Synthesis of sibutramine, a novel cyclobutylalkylamine useful in the treatment of obesity, and its major human metabolites","volume":"1","author":"Jeffery","year":"1996","journal-title":"J Chem Soc Perkin Trans"},{"key":"10.1002\/jps.23271_bb0090","doi-asserted-by":"crossref","first-page":"15914","DOI":"10.1021\/jp9043804","article-title":"Vibrational spectroscopy of secondary amine salts: 1. Assignment of NH2+ stretching frequencies in crystalline phases","volume":"113","author":"Giffin","year":"2009","journal-title":"J Phys Chem B"},{"key":"10.1002\/jps.23271_bb0095","series-title":"Atlas of plastics additives: Analysis by spectrometric methods","author":"Hummel","year":"2002"},{"key":"10.1002\/jps.23271_bb0100","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0022-2860(02)00580-X","article-title":"Infrared and Raman studies of water molecule normal vibrations in crystalline hydrates which form the chain structures","volume":"646","author":"Pieszczek","year":"2003","journal-title":"J Mol Struct"},{"key":"10.1002\/jps.23271_bb0105","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.carres.2011.01.026","article-title":"1H NMR study of rehydration\/dehydration and water mobility in \u03b2\u2010cyclodextrin","volume":"346","author":"Pajzderska","year":"2011","journal-title":"Carbohydrate Res"},{"key":"10.1002\/jps.23271_bb0110","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1080\/00268977700102891","article-title":"Proton magnetic relaxation and molecular motion in polycrystalline amino acids","volume":"34","author":"Andrew","year":"1977","journal-title":"Mol Phys"},{"key":"10.1002\/jps.23271_bb0115","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0926-2040(97)00077-5","article-title":"Molecular dynamics in solid l\u2010adrenaline by proton NMR","volume":"10","author":"Andrew","year":"1998","journal-title":"Solid State Nucl Magn Reson"},{"key":"10.1002\/jps.23271_bb0120","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0926-2040(99)00009-0","article-title":"Molecular dynamics in solid anhydrous\u2010estradiol studied by 1H NMR","volume":"14","author":"Andrew","year":"1999","journal-title":"Solid State Nucl Magn Reson"},{"key":"10.1002\/jps.23271_bb0125","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1002\/jps.21471","article-title":"NMR search for polymorphic phase transformations in chlorpropamide form\u2010A at high pressures","volume":"98","author":"Wasicki","year":"2009","journal-title":"J Pharm Sci"},{"key":"10.1002\/jps.23271_bb0130","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ijpharm.2010.10.044","article-title":"A hybrid method for estimation of molecular dynamics of diazepam\u2010density functional theory combined with NMR and FT\u2010IR spectroscopy","volume":"404","author":"Mielcarek","year":"2011","journal-title":"Int J Pharm"},{"key":"10.1002\/jps.23271_bb0135","article-title":"Konformacjionyj analiz organiczeskich molekul","author":"Daszewski","year":"1982","journal-title":"Moskwa Chimia"},{"key":"10.1002\/jps.23271_bb0140","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1103\/PhysRev.74.1168","article-title":"The dipolar broadening of magnetic resonance lines in crystals","volume":"74","author":"Van Vleck","year":"1948","journal-title":"Phys Rev"},{"key":"10.1002\/jps.23271_bb0145","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0926-2040(98)00082-4","article-title":"Calculation of the NMR second moment for materials with different types of internal rotation","volume":"13","author":"Goc","year":"1998","journal-title":"Solid State Nucl Magn Reson"},{"key":"10.1002\/jps.23271_bb0150","series-title":"Principles of magnetic resonance, 3rd enlarged and updated ed","author":"Slichter","year":"1996"}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915314039?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915314039?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T00:01:00Z","timestamp":1542844860000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022354915314039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":29,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0022354915314039"],"URL":"https:\/\/doi.org\/10.1002\/jps.23271","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}