{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T06:03:44Z","timestamp":1790143424460,"version":"4.0.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1002\/jps.24623","type":"journal-article","created":{"date-parts":[[2015,8,26]],"date-time":"2015-08-26T22:25:51Z","timestamp":1440627951000},"page":"4099-4108","source":"Crossref","is-referenced-by-count":21,"title":["Batch Statistical Process Monitoring Approach to a Cocrystallization Process"],"prefix":"10.1016","volume":"104","author":[{"given":"Mafalda C.","family":"Sarragu\u00e7a","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo R.S.","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adenilson O.","family":"Dos Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o A.","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1002\/jps.24623_bb0005","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1021\/cg3017112","article-title":"Green synthesis of ibuprofennicotinamide cocrystals and in-line evaluation by Raman spectroscopy","volume":"13","author":"Soares","year":"2013","journal-title":"Cryst Growth Des"},{"issue":"2","key":"10.1002\/jps.24623_bb0010","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1021\/cg401662d","article-title":"Furosemide cocrystals: Structures, hydrogen bonding, and implications for properties","volume":"14","author":"Harriss","year":"2014","journal-title":"Cryst Growth Des"},{"issue":"5","key":"10.1002\/jps.24623_bb0015","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1021\/cg3002948","article-title":"Polymorphs, salts, and cocrystals: What\u2019s in a name?","volume":"12","author":"Aitipamula","year":"2012","journal-title":"Cryst Growth Des"},{"issue":"1","key":"10.1002\/jps.24623_bb0020","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ejps.2009.05.010","article-title":"Formation of indomethacin-saccharin cocrystals using supercritical fluid technology","volume":"38","author":"Padrela","year":"2009","journal-title":"Eur J Pharm Sci"},{"issue":"3","key":"10.1002\/jps.24623_bb0025","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1021\/cg4019037","article-title":"Polymorphic cocrystals of nutraceutical compound p-coumaric acid with nicotinamide: Characterization, relative solid-state stability, and conversion to alternate stoichiometries","volume":"14","author":"Bevill","year":"2014","journal-title":"Cryst Growth Des"},{"issue":"4","key":"10.1002\/jps.24623_bb0030","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1021\/cg100098z","article-title":"Conformational and synthon polymorphism in furosemide (Lasix)","volume":"10","author":"Babu","year":"2010","journal-title":"Cryst Growth Des"},{"issue":"2","key":"10.1002\/jps.24623_bb0035","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1002\/jps.22805","article-title":"Novel furosemide cocrystals and selection of high solubility drug forms","volume":"101","author":"Goud","year":"2012","journal-title":"J Pharm Sci"},{"issue":"1","key":"10.1002\/jps.24623_bb0040","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.micromeso.2011.07.007","article-title":"MCM-41 for furosemide dissolution improvement","volume":"147","author":"Ambrogi","year":"2012","journal-title":"Micropor Mesopor Mater"},{"issue":"12","key":"10.1002\/jps.24623_bb0045","doi-asserted-by":"crossref","first-page":"5396","DOI":"10.1021\/cg2009946","article-title":"Naproxen cocrystals with pyridinecarboxamide isomers","volume":"11","author":"Castro","year":"2011","journal-title":"Cryst Growth Des"},{"issue":"23","key":"10.1002\/jps.24623_bb0050","doi-asserted-by":"crossref","first-page":"8193","DOI":"10.1039\/c2ce26151k","article-title":"Polymorphism and phase transformations of a cocrystal of nicotinamide and pimelic acid","volume":"14","author":"Aitipamula","year":"2012","journal-title":"CrystEngComm"},{"issue":"15","key":"10.1002\/jps.24623_bb0055","doi-asserted-by":"crossref","first-page":"3141","DOI":"10.1039\/C4CE00012A","article-title":"Structure determination of the theophylline-nicotinamide cocrystal: A combined powder XRD, 1D solid-state NMR, and theoretical calculation study","volume":"16","author":"Li","year":"2014","journal-title":"CrystEngComm"},{"key":"10.1002\/jps.24623_bb0060","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.supflu.2013.07.008","article-title":"Naproxen-nicotinamide cocrystals produced by CO2 antisolvent","volume":"83","author":"Neurohr","year":"2013","journal-title":"J Supercrit Fluids"},{"issue":"3","key":"10.1002\/jps.24623_bb0065","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.ejpb.2012.10.005","article-title":"In situ monitoring of carbamazepine-nicotinamide cocrystal intrinsic dissolution behaviour","volume":"83","author":"Qiao","year":"2013","journal-title":"Eur J Pharm Biopharm"},{"key":"10.1002\/jps.24623_bb0070","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.fluid.2013.11.024","article-title":"Solubility of carbamazepine, nicotinamide and carbamazepine-nicotinamide cocrystal in ethanol-water mixtures","volume":"363","author":"Shayanfar","year":"2014","journal-title":"Fluid Phase Equilib"},{"issue":"50","key":"10.1002\/jps.24623_bb0075","doi-asserted-by":"crossref","first-page":"18981","DOI":"10.1021\/ja4103887","article-title":"Cocrystals of nicotinamide and (R)-mandelic acid in many ratios with anomalous formation properties","volume":"135","author":"Zhang","year":"2013","journal-title":"J Am Chem Soc"},{"issue":"11","key":"10.1002\/jps.24623_bb0080","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1021\/op400182k","article-title":"Pharmaceutical cocrystals of diflunisal with nicotinamide or isonicotinamide","volume":"17","author":"Wang","year":"2013","journal-title":"Org Process Res Dev"},{"key":"10.1002\/jps.24623_bb0085","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.ejps.2014.06.001","article-title":"Generation of 1:1 carbamazepine:nicotinamide cocrystals by spray drying","volume":"62","author":"Patil","year":"2014","journal-title":"Eur J Pharm Sci"},{"issue":"1","key":"10.1002\/jps.24623_bb0090","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1021\/cg2013232","article-title":"Polymorphs and a hydrate of furosemide-nicotinamide 1:1 cocrystal","volume":"12","author":"Ueto","year":"2012","journal-title":"Cryst Growth Des"},{"issue":"1\u20132","key":"10.1002\/jps.24623_bb0095","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ijpharm.2011.12.033","article-title":"Monitoring ibuprofen-nicotinamide cocrystal formation during solvent free continuous cocrystallization (SFCC) using near infrared spectroscopy as a PAT tool","volume":"426","author":"Kelly","year":"2012","journal-title":"Int J Pharm"},{"key":"10.1002\/jps.24623_bb0100","series-title":"Guideline on the use of near infrared spectroscopy by the pharmaceutical industry and the data requirements for new submissions and variations","author":"European Medicines Agency (EMA)","year":"2014"},{"key":"10.1002\/jps.24623_bb0105","series-title":"Pharmaceutical development","author":"International Conference of Harmonization (ICH)","year":"2009"},{"issue":"1","key":"10.1002\/jps.24623_bb0110","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/cem.778","article-title":"Multivariate dynamic data modeling for analysis and statistical process control of batch processes, start-ups and grade transitions","volume":"17","author":"Kourti","year":"2003","journal-title":"J Chemom"},{"issue":"4","key":"10.1002\/jps.24623_bb0115","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/acs.859","article-title":"Application of latent variable methods to process control and multivariate statistical process control in industry","volume":"19","author":"Kourti","year":"2005","journal-title":"Int J Adapt Control Signal Process"},{"issue":"1\u20132","key":"10.1002\/jps.24623_bb0120","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.ijpharm.2013.04.039","article-title":"Application of in-line near infrared spectroscopy and multivariate batch modeling for process monitoring in fluid bed granulation","volume":"452","author":"Kona","year":"2013","journal-title":"Int J Pharm"},{"issue":"7","key":"10.1002\/jps.24623_bb0125","doi-asserted-by":"crossref","first-page":"3027","DOI":"10.1021\/cg2003029","article-title":"Quality by design (QbD)-based crystallization process development for the polymorphic drug tolbutamide","volume":"11","author":"Thirunahari","year":"2011","journal-title":"Cryst Growth Des"},{"key":"10.1002\/jps.24623_bb0130","series-title":"Guidance for industry: PAT\u2014A framework for innovative pharmaceutical development, manufacturing, and quality assurance","author":"Food and Drug Administration (FDA)","year":"2004"},{"issue":"5","key":"10.1002\/jps.24623_bb0135","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1002\/jps.23472","article-title":"Towards better process understanding: Chemometrics and multivariate measurements in manufacturing of solid dosage forms","volume":"102","author":"Matero","year":"2013","journal-title":"J Pharm Sci"},{"issue":"1\u20132","key":"10.1002\/jps.24623_bb0140","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.ijpharm.2014.06.003","article-title":"A PAT approach for the on-line monitoring of pharmaceutical co-crystals formation with near infrared spectroscopy","volume":"471","author":"Sarraguca","year":"2014","journal-title":"Int J Pharm"},{"key":"10.1002\/jps.24623_bb0145","series-title":"Principal component analysis","author":"Jolliffe","year":"2002"},{"issue":"1","key":"10.1002\/jps.24623_bb0150","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.talanta.2010.08.051","article-title":"A batch modelling approach to monitor a freezedrying process using in-line Raman spectroscopy","volume":"83","author":"Sarragu\u00e7a","year":"2010","journal-title":"Talanta"},{"issue":"1","key":"10.1002\/jps.24623_bb0155","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.molstruc.2006.04.021","article-title":"An experimental and theoretical study of vibrational spectra of picolinamide, nicotinamide, and isonicotinamide","volume":"826","author":"Bakiler","year":"2007","journal-title":"J Mol Struct"}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915000489?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915000489?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,20]],"date-time":"2018-09-20T00:57:58Z","timestamp":1537405078000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022354915000489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":31,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S0022354915000489"],"URL":"https:\/\/doi.org\/10.1002\/jps.24623","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]}}}