{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T16:22:21Z","timestamp":1777566141699,"version":"3.51.4"},"reference-count":64,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[1979,5,1]],"date-time":"1979-05-01T00:00:00Z","timestamp":294364800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[1979,5]]},"DOI":"10.1002\/jps.2600680505","type":"journal-article","created":{"date-parts":[[2006,10,15]],"date-time":"2006-10-15T08:57:11Z","timestamp":1160902631000},"page":"537-542","source":"Crossref","is-referenced-by-count":153,"title":["Anti-Inflammatory Activity of Sesquiterpene Lactones and Related Compounds"],"prefix":"10.1016","volume":"68","author":[{"given":"I.H.","family":"Hall","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.H.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.O.","family":"Starnes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Sumida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.Y.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.G.","family":"Waddell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.W.","family":"Cochran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.G.","family":"Gerhart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1002\/jps.2600680505_bb0005","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/223619a0","volume":"223","author":"Oronsky","year":"1969","journal-title":"Nature"},{"key":"10.1002\/jps.2600680505_bb0010","first-page":"334","volume":"14","author":"Lorber","year":"1966","journal-title":"Clin. Res."},{"key":"10.1002\/jps.2600680505_bb0015","doi-asserted-by":"crossref","first-page":"484","DOI":"10.3181\/00379727-132-34242","volume":"132","author":"Butler","year":"1969","journal-title":"Proc. Soc Exp.B iol. Med."},{"key":"10.1002\/jps.2600680505_bb0020","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1002\/art.1780090607","volume":"9","author":"Gerber","year":"1966","journal-title":"Arthritis Rheum."},{"key":"10.1002\/jps.2600680505_bb0025","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0006-2952(67)90192-X","volume":"16","author":"Gerber","year":"1967","journal-title":"Biochem. Pharmacol."},{"key":"10.1002\/jps.2600680505_bb0030","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1021\/jm00213a003","volume":"20","author":"Hall","year":"1977","journal-title":"J. Med. Chem."},{"key":"10.1002\/jps.2600680505_bb0035","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1126\/science.191909","volume":"196","author":"Lee","year":"1977","journal-title":"Science"},{"key":"10.1002\/jps.2600680505_bb0040","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/0005-2744(72)90011-3","volume":"276","author":"Smith","year":"1972","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1002\/jps.2600680505_bb0045","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1126\/science.168.3929.376","volume":"168","author":"Kupchan","year":"1970","journal-title":"Science"},{"key":"10.1002\/jps.2600680505_bb0050","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1126\/science.168.3929.378","volume":"168","author":"Hanson","year":"1970","journal-title":"Science"},{"key":"10.1002\/jps.2600680505_bb0055","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1002\/jps.2600670430","volume":"67","author":"Hall","year":"1978","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600680505_bb0060","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1002\/jps.2600670912","volume":"67","author":"Hall","year":"1978","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600680505_bb0065","series-title":"Pharmaceutical Botany","first-page":"561","author":"Kan","year":"1969"},{"key":"10.1002\/jps.2600680505_bb0070","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0031-9422(00)85153-5","volume":"9","author":"Lee","year":"1970","journal-title":"Phytochemistry"},{"issue":"626","key":"10.1002\/jps.2600680505_bb0075","volume":"61","author":"Lee","year":"1972","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600680505_bb0080","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1021\/jo01029a067","volume":"29","author":"Lucas","year":"1964","journal-title":"J. Org. Chem."},{"key":"10.1002\/jps.2600680505_bb0085","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1002\/jps.2600610432","volume":"61","author":"Lee","year":"1972","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600680505_bb0090","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1002\/jps.2600640656","volume":"64","author":"Lee","year":"1975","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600680505_bb0095","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/S0040-4039(00)93748-1","volume":"14","author":"Lee","year":"1976","journal-title":"Tetrahedron Lett."},{"key":"10.1002\/jps.2600680505_bb0100","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/S0031-9422(00)86734-5","volume":"16","author":"Lee","year":"1977","journal-title":"Phytochemistry"},{"key":"10.1002\/jps.2600680505_bb0105","doi-asserted-by":"crossref","unstructured":"K. H. Lee, H. Furukawa, M. Kozuka, H. C. Huang, P. A. Luchan, and A. T. McPhail, J. Chem. Soc., Chem. Commun., 1973,476.","DOI":"10.1039\/c39730000476"},{"key":"10.1002\/jps.2600680505_bb0110","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1002\/jps.2600640656","volume":"64","author":"Lee","year":"1975","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600680505_bb0115","doi-asserted-by":"crossref","unstructured":"A.T. McPhail, K. D. Onan, K. H. Lee, T. Ibuka, M. Kozuka, T., and T. G. Waddell, Shingu, and H. C. Huang, Tetrahedron Lett., 1974, 2739.","DOI":"10.1016\/S0040-4039(01)91728-9"},{"key":"10.1002\/jps.2600680505_bb0120","first-page":"1149","author":"Lee","year":"1974","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600680505_bb0125","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1021\/jm00276a010","volume":"15","author":"Lee","year":"1972","journal-title":"J. Med. Chem."},{"key":"10.1002\/jps.2600680505_bb0130","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1021\/jm00235a013","volume":"18","author":"Lee","year":"1975","journal-title":"J. Med. Chem."},{"key":"10.1002\/jps.2600680505_bb0135","unstructured":"T. G. Waddell, A. M. Austin, J. W. Cochran, K. G. Gerhart, I. H., Hall, and K. H. Lee, J. Pharm. Sci., in press."},{"key":"10.1002\/jps.2600680505_bb0140","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1021\/jm00217a009","volume":"20","author":"Lee","year":"1977","journal-title":"J. Med. Chem."},{"key":"10.1002\/jps.2600680505_bb0145","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1021\/jm00242a010","volume":"18","author":"Lee","year":"1975","journal-title":"J. Med. Chem."},{"key":"10.1002\/jps.2600680505_bb0150","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1021\/jo00427a017","volume":"42","author":"Ksander","year":"1977","journal-title":"J. Org. Chem."},{"key":"10.1002\/jps.2600680505_bb0155","first-page":"114","volume":"179","author":"Roszkowski","year":"1971","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1002\/jps.2600680505_bb0160","doi-asserted-by":"crossref","first-page":"544","DOI":"10.3181\/00379727-111-27849","volume":"111","author":"Winter","year":"1962","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1002\/jps.2600680505_bb0165","first-page":"94","volume":"220","author":"Randall","year":"1976","journal-title":"Arch. fnt. Phormacodyn Ther."},{"key":"10.1002\/jps.2600680505_bb0170","first-page":"435","volume":"175","author":"Dewey","year":"1970","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1002\/jps.2600680505_bb0175","first-page":"237","volume":"125","author":"Hendershot","year":"1959","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1002\/jps.2600680505_bb0180","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0014-2999(76)90004-2","volume":"37","author":"Vingar","year":"1976","journal-title":"Euc J. Pharmacol."},{"key":"10.1002\/jps.2600680505_bb0185","doi-asserted-by":"crossref","first-page":"403","DOI":"10.4049\/jimmunol.85.4.403","volume":"85","author":"Waksman","year":"1960","journal-title":"J. Immunol."},{"key":"10.1002\/jps.2600680505_bb0190","doi-asserted-by":"crossref","first-page":"597","DOI":"10.3181\/00379727-127-32751","volume":"127","author":"Sancilio","year":"1968","journal-title":"Proc. SOC. Exp. Biol. Med."},{"key":"10.1002\/jps.2600680505_bb0195","first-page":"681","volume":"7","author":"Mota","year":"1964","journal-title":"Immunology"},{"key":"10.1002\/jps.2600680505_bb0200","first-page":"749","volume":"16","author":"Goose","year":"1969","journal-title":"Immunology"},{"key":"10.1002\/jps.2600680505_bb0205","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1021\/jm00270a005","volume":"16","author":"Buckle","year":"1973","journal-title":"J. Med. Chem."},{"key":"10.1002\/jps.2600680505_bb0210","first-page":"387,395","volume":"58","author":"Matsumura","year":"1976","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1002\/jps.2600680505_bb0215","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1126\/science.140.3565.405","volume":"140","author":"Jerne","year":"1963","journal-title":"Science"},{"key":"10.1002\/jps.2600680505_bb0220","first-page":"37","volume":"28","author":"Iaarashi","year":"1975","journal-title":"Immunology"},{"key":"10.1002\/jps.2600680505_bb0225","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.3181\/00379727-132-34383","volume":"132","author":"Uyeki","year":"1969","journal-title":"Proc. Exp. Biol. Med."},{"key":"10.1002\/jps.2600680505_bb0230","doi-asserted-by":"crossref","first-page":"190","DOI":"10.3181\/00379727-127-32653","volume":"127","author":"Crowle","year":"1968","journal-title":"Proc. Soc. Exp. Biol."},{"key":"10.1002\/jps.2600680505_bb0235","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/0021-8707(68)90087-7","volume":"42","author":"Crowle","year":"1968","journal-title":"J. Allergy"},{"key":"10.1002\/jps.2600680505_bb0240","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/S0015-0282(16)37269-7","volume":"21","author":"Baggett","year":"1970","journal-title":"Fertil. Steril"},{"key":"10.1002\/jps.2600680505_bb0245","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1021\/jm00258a004","volume":"17","author":"Hall","year":"1974","journal-title":"J. Med. Chem."},{"key":"10.1002\/jps.2600680505_bb0250","series-title":"First Fertility Conference on Congenital Malformations","first-page":"187","author":"Wilson","year":"1961"},{"key":"10.1002\/jps.2600680505_bb0255","first-page":"61","volume":"2","author":"Emmens","year":"1970","journal-title":"Methods Horm. Res."},{"key":"10.1002\/jps.2600680505_bb0260","first-page":"604","volume":"53","author":"Brodie","year":"1967","journal-title":"J. Castroenterol."},{"key":"10.1002\/jps.2600680505_bb0265","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1021\/jm00234a011","volume":"19","author":"Lang","year":"1976","journal-title":"J. Med. Chem"},{"key":"10.1002\/jps.2600680505_bb0270","series-title":"Statistical Methods","author":"Snedecor","year":"1956"},{"key":"10.1002\/jps.2600680505_bb0275","series-title":"Inflammation and Anti-inflammatories","author":"Arrigoni-Mantelli","year":"1977"},{"key":"10.1002\/jps.2600680505_bb0280","first-page":"138","volume":"11","author":"Chang","year":"1976","journal-title":"Annu. Rep. Med. Chem."},{"key":"10.1002\/jps.2600680505_bb0285","series-title":"The Immunological Basis of Connective Tissue Disorders","author":"Mellbye","year":"1975"},{"key":"10.1002\/jps.2600680505_bb0290","first-page":"152","volume":"12","author":"Davies","year":"1977","journal-title":"Annu. Rep. Med. Chem."},{"key":"10.1002\/jps.2600680505_bb0295","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1365-3083.1972.tb01813.x","volume":"1","author":"Munthe","year":"1972","journal-title":"Scand. J. Irnrnunol."},{"key":"10.1002\/jps.2600680505_bb0300","series-title":"The Immunological Basis of Connective Tissue Disorders","first-page":"17","author":"Hamerman","year":"1975"},{"key":"10.1002\/jps.2600680505_bb0305","first-page":"120","volume":"1","author":"Hurwitz","year":"1974","journal-title":"J. Rheum. (Suppl.)"},{"key":"10.1002\/jps.2600680505_bb0310","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1136\/ard.32.4.283","volume":"32","author":"Allison","year":"1973","journal-title":"Ann. Rheum. Dis."},{"key":"10.1002\/jps.2600680505_bb0315","first-page":"572","volume":"16","author":"Stastny","year":"1972","journal-title":"Arthritis Rheum."},{"key":"10.1002\/jps.2600680505_bb0320","first-page":"179","volume":"14","author":"Peter","year":"1971","journal-title":"Arthritis Rheum."}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002235491542605X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002235491542605X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T10:44:14Z","timestamp":1683629054000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002235491542605X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,5]]},"references-count":64,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1979,5]]}},"alternative-id":["S002235491542605X"],"URL":"https:\/\/doi.org\/10.1002\/jps.2600680505","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[1979,5]]}}}