{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:30:32Z","timestamp":1791160232037,"version":"4.1.0"},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1983,1,1]],"date-time":"1983-01-01T00:00:00Z","timestamp":410227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[1983,1]]},"DOI":"10.1002\/jps.2600720105","type":"journal-article","created":{"date-parts":[[2006,10,15]],"date-time":"2006-10-15T02:02:33Z","timestamp":1160877753000},"page":"17-22","source":"Crossref","is-referenced-by-count":199,"title":["Zero-Order Controlled-Release Polymer Matrices for Micro- and Macromolecules"],"prefix":"10.1016","volume":"72","author":[{"given":"Dean S.T.","family":"Hsieh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William D.","family":"Rhine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Langer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1002\/jps.2600720105_bb0005","first-page":"1","article-title":"Controlled Release Polymerie Formulations","author":"Paul","year":"1976"},{"key":"10.1002\/jps.2600720105_bb0010","series-title":"Advances in Experimental Medicine and Biology Series","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/978-1-4684-7239-4_2","article-title":"Controlled Release of Biologically Active Agents","volume":"47","author":"Baker","year":"1974"},{"key":"10.1002\/jps.2600720105_bb0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/00986448008912519","volume":"6","author":"Langer","year":"1980","journal-title":"Chem. Eng. Commun."},{"key":"10.1002\/jps.2600720105_bb0020","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1002\/jps.2600501018","volume":"50","author":"Higuchi","year":"1961","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600720105_bb0025","doi-asserted-by":"crossref","unstructured":"Ibid., 52, 1145 (1963).","DOI":"10.1002\/jps.2600521210"},{"key":"10.1002\/jps.2600720105_bb0030","first-page":"1459","volume":"54","author":"Desai","year":"1965","journal-title":"ibid."},{"key":"10.1002\/jps.2600720105_bb0035","first-page":"325","volume":"68","author":"Samulov","year":"1979","journal-title":"ibid."},{"key":"10.1002\/jps.2600720105_bb0040","first-page":"265","volume":"69","author":"Rhine","year":"1980","journal-title":"ibid."},{"key":"10.1002\/jps.2600720105_bb0045","first-page":"725","volume":"63","author":"Cobby","year":"1974","journal-title":"ibid."},{"key":"10.1002\/jps.2600720105_bb0050","doi-asserted-by":"crossref","unstructured":"Ibid., 63,732 (1974).","DOI":"10.1002\/jps.2600630517"},{"key":"10.1002\/jps.2600720105_bb0055","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/jps.2600660206","volume":"66","author":"Brooke","year":"1977","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600720105_bb0060","first-page":"163","volume":"66","author":"Lipper","year":"1977","journal-title":"ibid."},{"key":"10.1002\/jps.2600720105_bb0065","first-page":"177","article-title":"Controlled Release of Bioactive Materials","author":"Rhine","year":"1980"},{"key":"10.1002\/jps.2600720105_bb0070","first-page":"679","article-title":"Polymer Processes: Chemical Technology of Plastics, Resins, Rubbers, Adhesives and Fibers","author":"Garvin","year":"1956"},{"key":"10.1002\/jps.2600720105_bb0075","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1002\/jps.2600640806","volume":"64","author":"Borodkin","year":"1975","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600720105_bb0080","first-page":"83","article-title":"Controlled Release of Bioactive Materials","author":"Langer","year":"1980"},{"key":"10.1002\/jps.2600720105_bb0085","unstructured":"L. Brown, C. Wei, and R. Langer, J. Pharm. Sci., in press."},{"key":"10.1002\/jps.2600720105_bb0090","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/jbm.820150212","volume":"15","author":"Langer","year":"1981","journal-title":"J. Biomed. Mat. Res."}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915444557?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915444557?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T12:35:09Z","timestamp":1627907709000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022354915444557"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1983,1]]}},"alternative-id":["S0022354915444557"],"URL":"https:\/\/doi.org\/10.1002\/jps.2600720105","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[1983,1]]}}}