{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:46:31Z","timestamp":1762865191296},"reference-count":13,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1985,3,1]],"date-time":"1985-03-01T00:00:00Z","timestamp":478483200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[1985,3]]},"DOI":"10.1002\/jps.2600740320","type":"journal-article","created":{"date-parts":[[2006,10,14]],"date-time":"2006-10-14T20:44:29Z","timestamp":1160858669000},"page":"321-324","source":"Crossref","is-referenced-by-count":11,"title":["Kinetics of Drug Action in Disease States XII: Effect of Experimental Liver Diseases on the Pharmacodynamics of Phenobarbital and Ethanol in Rats"],"prefix":"10.1016","volume":"74","author":[{"given":"Meindert","family":"Danhof","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masafumi","family":"Hisaoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerhard","family":"Levy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1002\/jps.2600740320_bb001","first-page":"53","article-title":"\"The Effect of Disease States on Drug Pharmacokinetics\"","author":"Rowland","year":"1976"},{"key":"10.1002\/jps.2600740320_bb002","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3109\/00498257709036242","volume":"7","author":"Kato","year":"1977","journal-title":"Xenobiotica"},{"key":"10.1002\/jps.2600740320_bb003","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1056\/NEJM198312293092605","volume":"309","author":"Williams","year":"1983","journal-title":"New Engl. J. Med."},{"key":"10.1002\/jps.2600740320_bb004","first-page":"43","article-title":"\"Topics in Pharmaceutical Sciences\"","author":"Levy","year":"1983"},{"key":"10.1002\/jps.2600740320_bb005","first-page":"7","volume":"131","author":"McLuen","year":"1961","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1002\/jps.2600740320_bb006","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/0006-2952(76)90479-2","volume":"25","author":"Drew","year":"1976","journal-title":"Biochem. Pharmacol."},{"key":"10.1002\/jps.2600740320_bb007","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1007\/BF01468101","volume":"51","author":"Zilly","year":"1973","journal-title":"Klin. Wochenschr."},{"key":"10.1002\/jps.2600740320_bb008","first-page":"44","volume":"229","author":"Danhof","year":"1984","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1002\/jps.2600740320_bb009","author":"Hisaoka","year":"1985","journal-title":"\"J. Pharmacol. Exp. Ther.\""},{"key":"10.1002\/jps.2600740320_bb0010","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S0021-9258(18)57021-6","volume":"177","author":"Gornall","year":"1949","journal-title":"J. Biol. Chem."},{"key":"10.1002\/jps.2600740320_bb0011","first-page":"627","volume":"230","author":"Danhof","year":"1984","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1002\/jps.2600740320_bb0012","unstructured":"Danhof, M.; Levy, G. J. Pharrnacol. Exp. Ther., in press."},{"key":"10.1002\/jps.2600740320_bb0013","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/0016-5085(83)90203-2","volume":"84","author":"Horowitz","year":"1983","journal-title":"Gastroenterology"}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915466420?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915466420?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T12:06:47Z","timestamp":1627906007000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022354915466420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,3]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1985,3]]}},"alternative-id":["S0022354915466420"],"URL":"https:\/\/doi.org\/10.1002\/jps.2600740320","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[1985,3]]}}}