{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:48:54Z","timestamp":1786978134882,"version":"build-2736575974"},"reference-count":19,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[1985,6,1]],"date-time":"1985-06-01T00:00:00Z","timestamp":486432000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[1985,6]]},"DOI":"10.1002\/jps.2600740605","type":"journal-article","created":{"date-parts":[[2006,10,14]],"date-time":"2006-10-14T17:04:19Z","timestamp":1160845459000},"page":"608-611","source":"Crossref","is-referenced-by-count":81,"title":["Mechanism of Nasal Absorption of Drugs I: Physicochemical Parameters Influencing the Rate of In Situ Nasal Absorption of Drugs in Rats"],"prefix":"10.1016","volume":"74","author":[{"given":"Chong Heng","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryohei","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rima Bawarshi","family":"Nassar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anwar","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1002\/jps.2600740605_bb0005","series-title":"U.S. Pharmacopeia","first-page":"579","year":"1980"},{"key":"10.1002\/jps.2600740605_bb0010","series-title":"Physician's Desk Reference","first-page":"592","year":"1983"},{"key":"10.1002\/jps.2600740605_bb0015","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1002\/jps.2600680942","volume":"68","author":"Hussain","year":"1979","journal-title":"J. Pharm. Sci"},{"key":"10.1002\/jps.2600740605_bb0020","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1002\/jps.2600691215","volume":"69","author":"Hussain","year":"1980","journal-title":"J. Pharm. Sci"},{"key":"10.1002\/jps.2600740605_bb0025","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1002\/jps.2600691037","volume":"69","author":"Hussain","year":"1980","journal-title":"J. Pharm. Sci"},{"key":"10.1002\/jps.2600740605_bb0030","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1002\/jps.2600700435","volume":"70","author":"Hussain","year":"1981","journal-title":"J. Pharm. Sci"},{"key":"10.1002\/jps.2600740605_bb0035","author":"Bawarshi","year":"1981"},{"key":"10.1002\/jps.2600740605_bb0040","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0378-5173(84)90097-8","volume":"21","author":"Hussain","year":"1984","journal-title":"Int. J. Pharm"},{"key":"10.1002\/jps.2600740605_bb0045","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1002\/jps.2600730929","volume":"73","author":"Hussain","year":"1984","journal-title":"J. Pharm. Sci"},{"key":"10.1002\/jps.2600740605_bb0050","doi-asserted-by":"crossref","first-page":"296","DOI":"10.2337\/diab.27.3.296","volume":"27","author":"Hirai","year":"1978","journal-title":"Diabetes"},{"key":"10.1002\/jps.2600740605_bb0055","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0378-5173(81)90010-7","volume":"9","author":"Hirai","year":"1981","journal-title":"Int. J. Pharm"},{"key":"10.1002\/jps.2600740605_bb0060","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0378-5173(81)90009-0","volume":"9","author":"Hirai","year":"1981","journal-title":"Int. J. Pharm"},{"key":"10.1002\/jps.2600740605_bb0065","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1002\/jps.2600730523","volume":"73","author":"Anik","year":"1984","journal-title":"J. Pharm. Sci"},{"key":"10.1002\/jps.2600740605_bb0070","unstructured":"Hussain, A., unpublished results."},{"key":"10.1002\/jps.2600740605_bb0075","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1002\/jps.2600730915","volume":"73","author":"Su","year":"1984","journal-title":"J. Pharm. Sci"},{"key":"10.1002\/jps.2600740605_bb0080","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0378-5173(81)90058-2","volume":"7","author":"Hirai","year":"1981","journal-title":"Int. J. Pharm"},{"key":"10.1002\/jps.2600740605_bb0085","author":"Huang","year":"1983"},{"key":"10.1002\/jps.2600740605_rf1015","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1248\/cpb.9.532","volume":"9","author":"Nogami","year":"1961","journal-title":"Chem. Pharm. Bull. (Tokyo)"},{"key":"10.1002\/jps.2600740605_rf5250","first-page":"4042h","volume":"56","year":"1962","journal-title":"Chem. Abstr"}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915467243?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915467243?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,21]],"date-time":"2019-04-21T15:30:20Z","timestamp":1555860620000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022354915467243"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,6]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1985,6]]}},"alternative-id":["S0022354915467243"],"URL":"https:\/\/doi.org\/10.1002\/jps.2600740605","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[1985,6]]}}}