{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T10:37:33Z","timestamp":1790332653161,"version":"4.1.0"},"reference-count":19,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[1992,8,1]],"date-time":"1992-08-01T00:00:00Z","timestamp":712627200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[1992,8]]},"DOI":"10.1002\/jps.2600810802","type":"journal-article","created":{"date-parts":[[2006,10,14]],"date-time":"2006-10-14T16:10:19Z","timestamp":1160842219000},"page":"731-735","source":"Crossref","is-referenced-by-count":94,"title":["Peptide Stability in Drug Development: A Comparison of Peptide Reactivity in Different Biological Media"],"prefix":"10.1016","volume":"81","author":[{"given":"Michael F.","family":"Powell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard","family":"Grey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Gaeta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Sette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Col\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1002\/jps.2600810802_bb0010","first-page":"56","article-title":"Buus, S. Sci. Am.","volume":"261","author":"Grey","year":"1989"},{"key":"10.1002\/jps.2600810802_bb0015","first-page":"2493","article-title":"J. Immunol","volume":"144","author":"Lamont","year":"1990"},{"key":"10.1002\/jps.2600810802_bb0020","first-page":"291","article-title":"Eur. J. Drug Metab. Pharmacokinet","volume":"11","author":"Verhoef","year":"1986"},{"key":"10.1002\/jps.2600810802_bb0025","first-page":"98","article-title":"Proc. Soc. Exp. Biol. Med","volume":"148","author":"Walter","year":"1975"},{"key":"10.1002\/jps.2600810802_bb0030","first-page":"377","article-title":"Neuroendocrinology","volume":"30","author":"Witter","year":"1980"},{"key":"10.1002\/jps.2600810802_bb0035","first-page":"557","article-title":"J. Endocrinol","volume":"110","author":"Verhoef","year":"1986"},{"key":"10.1002\/jps.2600810802_bb0040","first-page":"531","article-title":"Eur. J. Pharmacol","volume":"70","author":"Handa","year":"1981"},{"key":"10.1002\/jps.2600810802_bb0045","first-page":"251","article-title":"Eur. J. Biochem","volume":"122","author":"Bizzozero","year":"1982"},{"key":"10.1002\/jps.2600810802_bb0050","first-page":"217","article-title":"Eur. J. Biochem","volume":"151","author":"Chang","year":"1985"},{"key":"10.1002\/jps.2600810802_bb0055","first-page":"479","article-title":"Int. J. Protein Res","volume":"14","author":"Tischio","year":"1979"},{"key":"10.1002\/jps.2600810802_bb0060","first-page":"599","article-title":"Peptides","volume":"8","author":"Graf","year":"1987"},{"key":"10.1002\/jps.2600810802_bb0065","first-page":"247","article-title":"Peptides","volume":"7","author":"Scalia","year":"1986"},{"key":"10.1002\/jps.2600810802_bb0070","first-page":"257","article-title":"Peptides","volume":"6","author":"Benovitz","year":"1985"},{"key":"10.1002\/jps.2600810802_bb0075","first-page":"69","article-title":"Regul. Pept","volume":"2","author":"McDermott","year":"1981"},{"key":"10.1002\/jps.2600810802_bb0080","unstructured":"Chaplin, M., Syntex Research, personal communication"},{"key":"10.1002\/jps.2600810802_bb0085","first-page":"127","article-title":"Regul. Pept","volume":"4","author":"Koulischer","year":"1982"},{"key":"10.1002\/jps.2600810802_bb0090","first-page":"751","article-title":"Pharm. Res","volume":"7","author":"M\u00d8SS","year":"1990"},{"key":"10.1002\/jps.2600810802_bb0095","first-page":"906","article-title":"J. Clin. Invest","volume":"78","author":"Frohman","year":"1986"},{"key":"10.1002\/jps.2600810802_bb0100","first-page":"341","article-title":"Science","volume":"232","author":"Merrifield","year":"1986"}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915489087?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915489087?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,12]],"date-time":"2019-01-12T04:56:08Z","timestamp":1547268968000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022354915489087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,8]]},"references-count":19,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1992,8]]}},"alternative-id":["S0022354915489087"],"URL":"https:\/\/doi.org\/10.1002\/jps.2600810802","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[1992,8]]}}}