{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T21:49:36Z","timestamp":1761947376399},"reference-count":17,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[1995,6,1]],"date-time":"1995-06-01T00:00:00Z","timestamp":801964800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[1995,6]]},"DOI":"10.1002\/jps.2600840614","type":"journal-article","created":{"date-parts":[[2006,10,15]],"date-time":"2006-10-15T16:24:04Z","timestamp":1160929444000},"page":"733-736","source":"Crossref","is-referenced-by-count":39,"title":["A Novel Skeletal Drug Delivery System Using Self\u2010Setting Calcium Phosphate Cement. 9: Effects of the Mixing Solution Volume on Anticancer Drug Release from Homogeneous Drug-Loaded Cement"],"prefix":"10.1016","volume":"84","author":[{"given":"Makoto","family":"Otsuka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihisa","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey L.","family":"Fox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William I.","family":"Higuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1002\/jps.2600840614_bb0005","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/00003086-198606000-00015","volume":"207","author":"Salvati","year":"1986","journal-title":"Clin. Orthop."},{"key":"10.1002\/jps.2600840614_bb0010","doi-asserted-by":"crossref","first-page":"752","DOI":"10.2106\/00004623-197860060-00004","volume":"60A","author":"Petty","year":"1978","journal-title":"Jt. Surg. Am."},{"key":"10.1002\/jps.2600840614_bb0015","series-title":"Science and Medical Applications of Hydroxyapatite","first-page":"1","author":"Aoki","year":"1991"},{"key":"10.1002\/jps.2600840614_bb0020","doi-asserted-by":"crossref","first-page":"3500","DOI":"10.1248\/cpb.38.3500","volume":"38","author":"Otsuka","year":"1990","journal-title":"Chem. Pharm. Bull."},{"key":"10.1002\/jps.2600840614_bb0025","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1002\/jps.2600810611","volume":"81","author":"Yu","year":"1992","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600840614_bb0030","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1002\/jps.2600830230","volume":"83","author":"Otsuka","year":"1994","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600840614_bb0035","first-page":"173","volume":"3","author":"Otsuka","year":"1994","journal-title":"Pharm. Pharmacol. Lett."},{"key":"10.1002\/jps.2600840614_bb0040","first-page":"183","volume":"3","author":"Otsuka","year":"1994","journal-title":"Pharm. Pharmacol. Lett."},{"key":"10.1002\/jps.2600840614_bb0045","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1002\/jps.2600830502","volume":"83","author":"Otsuka","year":"1994","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600840614_bb0050","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/jps.2600830229","volume":"83","author":"Otsuka","year":"1994","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600840614_bb0055","unstructured":"Brown, W. E.; Chow, C. L.U.S. Patent 4 612 053, 1986."},{"key":"10.1002\/jps.2600840614_bb0060","doi-asserted-by":"crossref","first-page":"240","DOI":"10.2330\/joralbiosci1965.31.240","volume":"31","author":"Takezawa","year":"1989","journal-title":"Jpn. J. Oral Biol."},{"key":"10.1002\/jps.2600840614_bb0065","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1002\/jps.2600790611","volume":"79","author":"Wong","year":"1990","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600840614_bb0070","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1111\/j.1151-2916.1991.tb07176.x","volume":"74","author":"Kokubo","year":"1991","journal-title":"J. Am. Ceram. Soc."},{"key":"10.1002\/jps.2600840614_bb0075","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1002\/jps.2600521210","volume":"52","author":"Higuchi","year":"1963","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600840614_bb0080","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1002\/jps.2600630516","volume":"63","author":"Cobby","year":"1974","journal-title":"J. Pharm. Sci."},{"key":"10.1002\/jps.2600840614_bb0085","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1248\/bpb1978.4.879","volume":"4","author":"Yamaoka","year":"1981","journal-title":"J. Pharmacbio\u2013Dyn."}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915498284?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354915498284?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T11:06:09Z","timestamp":1683630369000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022354915498284"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,6]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1995,6]]}},"alternative-id":["S0022354915498284"],"URL":"https:\/\/doi.org\/10.1002\/jps.2600840614","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[1995,6]]}}}