{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:40:43Z","timestamp":1760920843740,"version":"build-2065373602"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T00:00:00Z","timestamp":1575504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Intramuscular fat (IMF) and polyunsaturated fatty acids (PUFAs) have been thought to play a crucial role in improving meat quality. Considering the ability of pioglitazone hydrochloride (PGZ) to deposit fat, and the anti\u2010stress capability of chromium methionine (CrMet), we combined these compounds to produce higher quality meat in poultry. A total of 3000 female chickens were divided into four groups (five replicates, each with 150 chickens): control, control plus15\u2009mg\u00b7kg<jats:sup>\u22121<\/jats:sup> PGZ, control plus 200\u2009\u03bcg\u00b7kg<jats:sup>\u22121<\/jats:sup> CrMet, and control plus15\u2009mg\u00b7kg<jats:sup>\u22121<\/jats:sup> PGZ\u2009plus\u2009200\u2009\u03bcg\u00b7kg<jats:sup>\u22121<\/jats:sup> CrMet. The experiment lasted for 28\u2009days.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Compared to the control group and the PGZ group, the average daily gain (ADG) was significantly increased in the PGZ\u2009plus\u2009CrMet group, whereas the feed\u2010to\u2010gain ratio (F\/G) was decreased from 0 to 14\u2009days. Meanwhile, the redness value of breast muscle and IMF of thigh muscle increased in the PGZ\u2009plus\u2009CrMet group compared with the control group and these detections in the PGZ\u2009plus\u2009CrMet group exhibited highest value among the four groups. The cooking loss decreased in the breast muscle and thigh muscle after PGZ combined with CrMet in diets. The percentages of C16:1, C18:2n\u20106 and PUFAs increased in the PGZ\u2009plus\u2009CrMet group. The mRNA abundance of peroxisome proliferator activated receptor (PPAR) <jats:italic>\u03b3<\/jats:italic>, PPAR coactivator 1 <jats:italic>\u03b1<\/jats:italic>, and fatty acid binding protein 3 was significantly enhanced with PGZ\u2009plus\u2009CrMet supplementation.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Collectively, dietary supplementation with PGZ\u2009plus\u2009CrMet improved growth performance and meat quality by decreasing the cooking loss and increasing the IMF and PUFA levels. \u00a9 2019 Society of Chemical Industry<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.10146","type":"journal-article","created":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T13:10:05Z","timestamp":1574169005000},"page":"1311-1319","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Dietary supplementation with pioglitazone hydrochloride and chromium methionine manipulates lipid metabolism with related genes to improve the intramuscular fat and fatty acid profile of yellow\u2010feathered chickens"],"prefix":"10.1002","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4475-4595","authenticated-orcid":false,"given":"Cheng\u2010long","family":"Jin","sequence":"first","affiliation":[{"name":"College of Animal Science South China Agricultural University\/Guangdong Provincial Key Laboratory of Animal Nutrition Control\/Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture Guangzhou  Guangzhou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huan\u2010ren","family":"Zeng","sequence":"additional","affiliation":[{"name":"College of Animal Science South China Agricultural University\/Guangdong Provincial Key Laboratory of Animal Nutrition Control\/Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture Guangzhou  Guangzhou Guangdong 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