{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T22:02:24Z","timestamp":1790287344425,"version":"4.1.0"},"reference-count":46,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T00:00:00Z","timestamp":1598572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100011647","name":"Universidade Federal de Lavras","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011647","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"CAPES","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Nutritional intervention with the use of phytochemicals is an important method for the treatment and prevention of a metabolic syndrome. The objective of this study was to chemically characterize Moro orange juice. The influence of juice intake on metabolic parameters of rats that were obese, diabetic or both by means of body mass management after the activation of anthocyanins during refrigerated storage was also assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Juice intake reversed most of the metabolic abnormalities exhibited by obese rats, including reduction of body mass and improvement of the biochemical profile. The loss of body mass by diabetic animals and obese and diabetic animals was not attributed to juice intake, but to type I diabetes mellitus. In these animals, no improvement was observed in the biochemical profile, liver enzymes and glycemia, so this treatment model was deemed unfeasible.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>The beneficial effects cannot be explained only by the anthocyanin C3G present in the juice, but rather, by the synergism between all the components. Studies in humans are needed to determine whether the ingestion of this orange can be recommended as an effective strategy to prevent or ameliorate complications of obesity. \u00a9 2020 Society of Chemical Industry<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.10714","type":"journal-article","created":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T00:04:25Z","timestamp":1596758665000},"page":"1053-1064","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effects of <scp>Moro<\/scp> orange juice (<i>Citrus sinensis<\/i><scp>(l.) Osbeck<\/scp>) on some metabolic and morphological parameters in obese and diabetic rats"],"prefix":"10.1002","volume":"101","author":[{"given":"Ma\u00edsa Lamounier","family":"Magalh\u00e3es","sequence":"first","affiliation":[{"name":"Department of Food Science\/DCA Universidade Federal de Lavras (UFLA)  Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raimundo Vicente","family":"de Sousa","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Universidade Federal de Lavras  Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Rafael","family":"Miranda","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Universidade Federal de Lavras  Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac Filipe Moreira","family":"Konig","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Universidade Federal de Lavras  Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flademir","family":"Wouters","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Universidade Federal de Lavras  Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda Rezende","family":"Souza","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Universidade Federal de Lavras  Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio Domingos","family":"Sim\u00e3o","sequence":"additional","affiliation":[{"name":"Department of Animal Science Universidade Federal de Lavras  Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan","family":"da Silva Lunguinho","sequence":"additional","affiliation":[{"name":"Department Chemistry\/DQI Universidade Federal de Lavras (UFLA)  Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7435-3675","authenticated-orcid":false,"given":"David Lee","family":"Nelson","sequence":"additional","affiliation":[{"name":"Department of Pro\u2010Rectory of Research and Graduate Studies Universidade Federal do Vale do Jequitinhonha e Mucuri  Diamantina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8075-1725","authenticated-orcid":false,"given":"Maria","family":"das Gra\u00e7as Cardoso","sequence":"additional","affiliation":[{"name":"Department Chemistry\/DQI Universidade Federal de Lavras (UFLA)  Lavras Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,28]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Varella D.S\u00edndrome metab\u00f3lica. Sociedade Brasileira de Endocrinologia e Metabologia 2018. Available:http:\/\/bvsms.saude.gov.br\/dicas-em-saude\/2610-sindrome-metabolica\/[24 October 2018]."},{"key":"e_1_2_6_3_1","unstructured":"WHO\u2013 World Health Organization.Overweight and obesity.2016. Available:https:\/\/www.who.int\/gho\/ncd\/risk_factors\/overweight_text\/en\/[24 January 2019]."},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/157240"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.7916"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/14786419.2014.1000897"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu9101089"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.4236\/ajps.2019.101003"},{"key":"e_1_2_6_9_1","first-page":"1","volume-title":"Official Methods of Analysis of the Association of Official Analytical Chemistry","author":"AOAC (Association of Oficial Analytical Chemistral)","year":"1992"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac60072a033"},{"key":"e_1_2_6_11_1","first-page":"56","volume-title":"The Orange: Its Biochemistry and Physiology","author":"Bitters WP","year":"1961"},{"key":"e_1_2_6_12_1","first-page":"477","volume-title":"Carbohydrate Chemistry","author":"Dische Z","year":"1962"},{"key":"e_1_2_6_13_1","first-page":"1","article-title":"Metodologia cient\u00edfica: determina\u00e7\u00e3o da atividade antioxidante total em frutas pela captura do radical livre DPPH","volume":"127","author":"Rufino MSM","year":"2007","journal-title":"Comun. T\u00e9c. Emb"},{"key":"e_1_2_6_14_1","first-page":"1","article-title":"Metodologia cient\u00edfica: determina\u00e7\u00e3o da atividade antioxidante total em frutas no sistema \u00df caroteno \u2013 \u00e1cido linol\u00e9ico","volume":"126","author":"Rufino MSM","year":"2006","journal-title":"Comun. T\u00e9c. Emb"},{"key":"e_1_2_6_15_1","first-page":"21","volume-title":"Currente Protocols in Food Analytical Chemistry","author":"Waterhouse AL","year":"2002"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.5876"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/0471142913.faf0102s00"},{"key":"e_1_2_6_18_1","first-page":"1","volume-title":"An\u00e1lises de Vitaminas: M\u00e9todos Comprovados","author":"Strohecker R","year":"1967"},{"key":"e_1_2_6_19_1","first-page":"365","article-title":"Radiographic evaluation of the effect of obesity on alveolar bone in rats with ligature\u2010induced periodontal diseases","volume":"7","author":"Nascimento CM","year":"2013","journal-title":"Diabetes Metab Syndr Obes"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpn.12452"},{"key":"e_1_2_6_21_1","first-page":"256","article-title":"Metabolic effects of \u03b2\u2010glucans (Saccharomycescerevisae) per os administration in rats with streptozotocin\u2010induced diabetes","volume":"32","author":"Lobato RV","year":"2015","journal-title":"Nutr Hosp"},{"key":"e_1_2_6_22_1","first-page":"1","article-title":"Benefits of fish oil consumption over other sources of lipids on metabolic parameters in obese rats","volume":"10","author":"Godim PN","year":"2018","journal-title":"Nutrients"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-89132013000500015"},{"key":"e_1_2_6_24_1","volume-title":"Medi\u00e7\u00e3o Tridimensional de Estereologia Imparcial em Microscopia","author":"Howard CV","year":"1998"},{"key":"e_1_2_6_25_1","first-page":"2","volume-title":"Diretriz Brasileira sobre Dislipidemias e Preven\u00e7\u00e3o da Aterosclerose","author":"Sposito AC","year":"1997"},{"key":"e_1_2_6_26_1","first-page":"98","volume-title":"Pediatric Reference Intervals","author":"Soldin SJ","year":"2005"},{"key":"e_1_2_6_27_1","unstructured":"R Core Team. R: ALanguage and Environment for Statistical Computing. R Foundation for Statistical Computing 2018. Available:http:\/\/www.R-project.org\/[25 September 2018]."},{"key":"e_1_2_6_28_1","first-page":"51","article-title":"Influ\u00eancia do armazenamento refrigerado de frutos de laranjeiras sangu\u00edneas quanto as suas caracter\u00edsticas f\u00edsico\u2010qu\u00edmicas e concentra\u00e7\u00e3o de antocianinas","volume":"29","author":"Latado RR","year":"2008","journal-title":"Laranja"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.postharvbio.2008.02.002"},{"key":"e_1_2_6_30_1","first-page":"1","article-title":"Fisiologia e manejo p\u00f3s\u2010colheita de frutas de clima temperado","volume":"2","author":"Kluge RA","year":"2002","journal-title":"Campinas: Livraria e Editora Rural"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2621.2006.tb08901.x"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-1296.58155"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0889-1575(90)90004-6"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf051609s"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2008.04.054"},{"key":"e_1_2_6_36_1","first-page":"67","article-title":"Teor de fen\u00f3licos totais e capacidade antioxidante de polpas congeladas de frutas","volume":"19","author":"Melo EA","year":"2008","journal-title":"Alim Nutr Araraquara"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2009.266"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7FO02061A"},{"key":"e_1_2_6_39_1","first-page":"195","article-title":"Avalia\u00e7\u00e3o da Import\u00e2ncia da Associa\u00e7\u00e3o dos Diab\u00e9ticos para a Popula\u00e7\u00e3o de uma Cidade do Estado de Goi\u00e1s","volume":"20","author":"Silva JR","year":"2016","journal-title":"Revista Ensaios e Ci\u00eancia: Ci\u00eancias Biol\u00f3gicas, Agr\u00e1rias e Sa\u00fade"},{"key":"e_1_2_6_40_1","unstructured":"GuerraM Por que o diabetes fora de controle pode causar muita sede ou fome?Available:https:\/\/cuidadospelavida.com.br\/saude-e-tratamento\/diabetes\/por-que-diabetes-fora-de-controle-pode-fome-sede[24 January2019]."},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2010.12.013"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf073113b"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ramd.2014.11.004"},{"key":"e_1_2_6_44_1","first-page":"159","article-title":"O papel da linha\u00e7a como agente redutor de colesterol e perda de peso","volume":"11","author":"Tonetta V","year":"2017","journal-title":"Revista Brasileira de Obesidade, Nutri\u00e7\u00e3o e Emagrecimento"},{"key":"e_1_2_6_45_1","first-page":"59","article-title":"Ingest\u00e3o regular do suco de laranja vermelha reduz press\u00e3o arterial de adultos","volume":"30","author":"Lima CG","year":"2012","journal-title":"Revista do Instituto de Ci\u00eancias da Saude (UNIP)"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i29.3862"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0196912"}],"container-title":["Journal of the Science of Food and Agriculture"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjsfa.10714","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jsfa.10714","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jsfa.10714","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jsfa.10714","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T08:55:11Z","timestamp":1760864111000},"score":1,"resource":{"primary":{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/10.1002\/jsfa.10714"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,28]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1002\/jsfa.10714"],"URL":"https:\/\/doi.org\/10.1002\/jsfa.10714","archive":["Portico"],"relation":{},"ISSN":["0022-5142","1097-0010"],"issn-type":[{"value":"0022-5142","type":"print"},{"value":"1097-0010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,28]]},"assertion":[{"value":"2019-08-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}