{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T18:34:56Z","timestamp":1785177296604,"version":"3.55.0"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,10,17]],"date-time":"2020-10-17T00:00:00Z","timestamp":1602892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Tetracycline antibiotics are employed for human and animal health and for speeding up growth rates. However, their presence in food products and environmental waters has been a concern for some years. Therefore, a variety of sample preparation methods have been developed for the analysis of tetracycline residues in these matrices.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>An electrochemically controlled solid phase microextraction based on a modified copper electrode with polyaniline\/graphene oxide (PANI\/GO) conductive nanocomposite was developed for the extraction of oxytetracycline, tetracycline and doxycycline before high\u2010performance liquid chromatography\u2010UV analysis. PANI\/GO was synthesized by <jats:italic>in situ<\/jats:italic> chemical oxidative polymerization, characterized by scanning electron microscopy and Fourier\u2010transform infrared spectroscopy, and bound on the electrode using high purity conductive double\u2010sided adhesive carbon glue. The significant factors affecting the performance of microextraction were investigated and optimized. Under the optimized conditions [sample, 15\u2009mL; sorbent, 10 mg; pH, 3.0; electroextraction voltage, \u22120.9 V; electroextraction time, 20\u2009min; eluent (MeOH\/NH<jats:sub>3<\/jats:sub>), 500\u2009\u03bcL; and desorption time, 5 min], the limits of detection for target analytes were in the ranges 0.32\u20131.01 and 2.42\u20137.59\u2009\u03bcg\u2009L<jats:sup>\u22121<\/jats:sup> in water and milk samples, respectively. The linear ranges were 1.06\u2013750\u2009\u03bcg\u2009L<jats:sup>\u22121<\/jats:sup> for water and 8.05\u2013750\u2009\u03bcg\u2009L<jats:sup>\u22121<\/jats:sup> for milk samples. The intra\u2010day and inter\u2010day precisions were 2.32\u20133.80 and 3.29\u20134.25, respectively. The method was applied to the determination of analytes in milk and water samples with different fat contents, and the recoveries were obtained in the range 71\u2013104%.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>The developed electro\u2010microextraction method provides a facile, rapid, cost\u2010effective, sensitive and efficient promising procedure for the extraction of antibiotics in complex matrices. \u00a9 2020 Society of Chemical Industry<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.10851","type":"journal-article","created":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T06:14:12Z","timestamp":1601619252000},"page":"2304-2311","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Electrochemically controlled solid phase microextraction based on a conductive polyaniline\u2010graphene oxide nanocomposite for extraction of tetracyclines in milk and water"],"prefix":"10.1002","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6300-1954","authenticated-orcid":false,"given":"Hassan","family":"Sereshti","sequence":"first","affiliation":[{"name":"School of Chemistry, College of Science University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faezeh","family":"Karami","sequence":"additional","affiliation":[{"name":"School of Chemistry, College of Science University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Nouri","sequence":"additional","affiliation":[{"name":"School of Chemistry, College of Science University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Farahani","sequence":"additional","affiliation":[{"name":"School of Chemistry, College of Science University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2018.10.011"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/10410236.2014.943634"},{"key":"e_1_2_6_4_1","unstructured":"US Code of Federal Regulations.Title 21 Part556 Sections 150 500 and 700. 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