{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T03:13:43Z","timestamp":1792120423552,"version":"4.4.0"},"reference-count":157,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T00:00:00Z","timestamp":1626220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Turmeric (\n                    <jats:italic>Curcuma longa<\/jats:italic>\n                    L.) is a spice utilized widely in India, China, and Southeast Asia as an aromatic stimulant, a food preservative, and coloring material. The commonly used names of turmeric are castor saffron, turmeric, and saffron root. Turmeric is a yellow\u2013orange polyphenolic natural substance derived from\n                    <jats:italic>C. longa<\/jats:italic>\n                    rhizomes. It has been used to treat common inflammatory diseases, tumors, biliary diseases, anorexia, cough, topical wounds, diabetic injuries, liver disorders, rheumatism, and sinusitis. Extensive studies on the biological properties and pharmacological consequences of turmeric extracts have been conducted in recent years. Curcumin, the primary yellow biocomponent of turmeric, has anti\u2010inflammatory, antioxidant, anticarcinogenic, antidiabetic, antibacterial, antiprotozoal, antiviral, antifibrotic, immunomodulatory, and antifungal properties. Defense assessment tests showed that curcumin is tolerated well at high doses, without adverse effects. Thus, curcumin is a highly active biological material with the potential to treat different diseases in modern medicine. This review article focuses on curcumin's biological characteristics. The most popular methods for curcumin encapsulation are also discussed. Several effective techniques and approaches have been proposed for curcuminoid capsulation, including nanocomplexing, gelation, complex coacervation, electrospraying, and solvent\u2010free pH\u2010driven encapsulation. This review also highlights curcumin's chemical properties, allowing the readers to expand their perspectives on its use in the development of functional products with health\u2010promoting properties. \u00a9 2021 Society of Chemical Industry.\n                  <\/jats:p>","DOI":"10.1002\/jsfa.11372","type":"journal-article","created":{"date-parts":[[2021,6,18]],"date-time":"2021-06-18T13:03:40Z","timestamp":1624021420000},"page":"5747-5762","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":374,"title":["Curcumin, the active substance of turmeric: its effects on health and ways to improve its bioavailability"],"prefix":"10.1002","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2831-8534","authenticated-orcid":false,"given":"Mohamed E","family":"Abd El\u2010Hack","sequence":"first","affiliation":[{"name":"Department of Poultry Faculty of Agriculture, Zagazig University  Zagazig 44511 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Animal Wealth Development, Faculty of Veterinary Medicine Damanhour University  Damanhour 22511 Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Shukry","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Veterinary Medicine Kafrelsheikh University  Kafrelsheikh 33516 Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Noreldin","sequence":"additional","affiliation":[{"name":"Department of Histology and Cytology, Faculty of Veterinary Medicine Damanhour University  Damanhour 22511 Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0429-2587","authenticated-orcid":false,"given":"Ayman E","family":"Taha","sequence":"additional","affiliation":[{"name":"Department of Animal Husbandry and Animal Wealth Development, Faculty of Veterinary Medicine Alexandria University  Edfina 22758 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