{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T10:54:15Z","timestamp":1777287255329,"version":"3.51.4"},"reference-count":36,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T00:00:00Z","timestamp":1650585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31901687"],"award-info":[{"award-number":["31901687"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>An emulsion delivery system for benzyl isothiocyanate (BITC) was prepared using fish skin gelatin (FSG) and sodium alginate (Alg). The effects of the FSG\u2013Alg complex on the emulsion stability and BITC release pattern from the emulsion were investigated <jats:italic>in vitro<\/jats:italic> and <jats:italic>in vivo<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>The storage stability and embedding rate of the 10\u00a0g\u2009kg<jats:sup>\u22121<\/jats:sup> FSG and 2.5\u00a0g\u2009kg<jats:sup>\u22121<\/jats:sup> Alg (FSG\u2013Alg) emulsion were the highest among all samples. The FSG\u2013Alg complex provided BITC a better protection during <jats:italic>in vitro<\/jats:italic> digestion. The microstructure of the FSG\u2013Alg emulsions was more stable during <jats:italic>in vitro<\/jats:italic> digestion, and the bioaccessibility and retention rate of BITC were much higher compared to those of the FSG emulsion. The results of the <jats:italic>ex vivo<\/jats:italic> everted gut sac of rat intestine study showed that the FSG\u2013Alg emulsion significantly increased the BITC absorption rate in the duodenum.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>The FSG\u2013Alg emulsion delivery system is a highly stable system for the delivery of BITC that improves the bioaccessibility of BITC and promotes its absorption in the duodenum. \u00a9 2022 Society of Chemical Industry.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.11915","type":"journal-article","created":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T22:35:22Z","timestamp":1649284522000},"page":"5680-5689","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Influence of fish skin gelatin\u2013sodium alginate complex stabilized emulsion on benzyl isothiocyanate stability and digestibility <i>in vitro<\/i> and <i>in vivo<\/i>"],"prefix":"10.1002","volume":"102","author":[{"given":"Xiangyu","family":"Zhang","sequence":"first","affiliation":[{"name":"National Engineering Research Center of Seafood, School of Food Science and Technology Dalian Polytechnic University  Dalian P. 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