{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T18:59:49Z","timestamp":1776625189875,"version":"3.51.2"},"reference-count":47,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T00:00:00Z","timestamp":1663891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>The search for alternatives to sulfur dioxide (SO<jats:sub>2<\/jats:sub>) in white wine production is a tough challenge for the oenological industry. The current article investigates the effectiveness of several preservatives in protecting Verdejo white wines. The following wines were elaborated: without preservative (CT wines), with SO<jats:sub>2<\/jats:sub> (SO<jats:sub>2<\/jats:sub> wines), with stilbene\u2010enriched extract (ST99 wines), with glutathione (GSH wines) and finally with the combination stilbene extract plus glutathione (ST99\u2010GSH wines).<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>ST99 extract preserved the wines from malolactic fermentation (MLF), maintained the quality parameters of the wines, but affected their color from the beginning of the process. Synergistic effects between ST99 and GSH were found for oxygen consumption rates, related to oxidation processes. The content of amino acids and biogenic amines was slightly affected by the treatments, but the quality or safety of the wines was not compromised. However, after 12\u2009months of ageing in bottle, the SO<jats:sub>2<\/jats:sub> wines showed the highest score in the sensory analysis. The reasons for the evolution of treated wines and the implications of this study for maintaining the quality of free SO<jats:sub>2<\/jats:sub> white wines are discussed.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>ST99 may be proposed as an alternative to SO<jats:sub>2<\/jats:sub> in wines to be consumed in the short term. Its combination with GSH does not prolong its shelf\u2010life. \u00a9 2022 Society of Chemical Industry.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.12209","type":"journal-article","created":{"date-parts":[[2022,9,8]],"date-time":"2022-09-08T03:03:55Z","timestamp":1662606235000},"page":"1152-1160","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Sulfur dioxide\u2010free Verdejo wines through the use of a pure stilbene extract: exploring possible synergistic effect with glutathione"],"prefix":"10.1002","volume":"103","author":[{"given":"Roc\u00edo","family":"Guti\u00e9rrez\u2010Escobar","sequence":"first","affiliation":[{"name":"Instituto de Investigaci\u00f3n y Formaci\u00f3n Agraria, Pesquera Alimentaria y de la Producci\u00f3n Ecol\u00f3gica (IFAPA), Consejer\u00eda de Agricultura, Ganader\u00eda, Pesca y Desarrollo Sostenible, Rancho de la Merced, Ctra. Ca\u00f1ada de la Loba (CA\u20103102)  C\u00e1diz Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Alia\u00f1o\u2010Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n y Formaci\u00f3n Agraria, Pesquera Alimentaria y de la Producci\u00f3n Ecol\u00f3gica (IFAPA), Consejer\u00eda de Agricultura, Ganader\u00eda, Pesca y Desarrollo Sostenible, Rancho de la Merced, Ctra. Ca\u00f1ada de la Loba (CA\u20103102)  C\u00e1diz Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Almudena","family":"Marrufo\u2010Curtido","sequence":"additional","affiliation":[{"name":"Research and Development Department Bodegas Fundador, SLU Calle San Ildefonso  C\u00e1diz Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Jes\u00fas","family":"Jim\u00e9nez\u2010Hierro","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n y Formaci\u00f3n Agraria, Pesquera Alimentaria y de la Producci\u00f3n Ecol\u00f3gica (IFAPA), Consejer\u00eda de Agricultura, Ganader\u00eda, Pesca y Desarrollo Sostenible, Rancho de la Merced, Ctra. Ca\u00f1ada de la Loba (CA\u20103102)  C\u00e1diz Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bel\u00e9n","family":"Puertas","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n y Formaci\u00f3n Agraria, Pesquera Alimentaria y de la Producci\u00f3n Ecol\u00f3gica (IFAPA), Consejer\u00eda de Agricultura, Ganader\u00eda, Pesca y Desarrollo Sostenible, Rancho de la Merced, Ctra. Ca\u00f1ada de la Loba (CA\u20103102)  C\u00e1diz Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8560-8821","authenticated-orcid":false,"given":"Emma","family":"Cantos\u2010Villar","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n y Formaci\u00f3n Agraria, Pesquera Alimentaria y de la Producci\u00f3n Ecol\u00f3gica (IFAPA), Consejer\u00eda de Agricultura, Ganader\u00eda, Pesca y Desarrollo Sostenible, Rancho de la Merced, Ctra. Ca\u00f1ada de la Loba (CA\u20103102)  C\u00e1diz Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,9,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1533\/9781845699987.2.432"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2021.129689"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.5344\/ajev.2016.16006"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.5344\/ajev.2008.59.2.128"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods10081711"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.5b04634"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2009.03362.x"},{"key":"e_1_2_6_9_1","first-page":"4438","article-title":"Scientific Opinion on the re\u2010evaluation of sulfur dioxide (E 220), sodium sulfite (E 221), sodium bisulfite (E 222), sodium metabisulfite (E 223), potassium metabisulfite (E 224), calcium sulfite (E 226), calcium bisulfite (E 227) and potassium bisulfite","volume":"14","author":"EFSA","year":"2016","journal-title":"EFSA J"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2013.03.026"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lwt.2015.08.005"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fpsl.2018.10.008"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2011.06.014"},{"key":"e_1_2_6_14_1","first-page":"156","article-title":"Oxygen consumption in south African sauvignon blanc wines: role of glutathione, sulphur dioxide and certain phenolics","volume":"34","author":"Fracassetti D","year":"2013","journal-title":"South African J Enol Vitic"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2019.108594"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00217-014-2334-5"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lwt.2021.112318"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2014.03.031"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2020.107684"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods10020439"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.3674"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26010232"},{"key":"e_1_2_6_23_1","unstructured":"Hidalgo Togores J. Tratado de enolog\u00eda I. MundiPrensa editor. Madrid; 2018. 1936 p."},{"key":"e_1_2_6_24_1","unstructured":"IOV IO of V and W.Resolution IOV\u2010OENO 445\u20102015 Tratamientos de los mostos con glutati\u00f3n. OENO 2015; 2."},{"key":"e_1_2_6_25_1","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1007\/978-1-4615-1781-8","volume-title":"Principles and Practices of Winemaking","author":"Boulton RB","year":"1996"},{"key":"e_1_2_6_26_1","unstructured":"IOV IO of V and W.Compendium of international methods of wine and must analysis. OENO 2021;1:673."},{"key":"e_1_2_6_27_1","unstructured":"IOV IO of V and W.Analysis of volatile compounds in wines by gas chromatography. Resolut (OIV\u2010OENO 553\/2016). 2016;1\u201311. Available:https:\/\/www.oiv.int\/public\/medias\/5159\/oiv-ma-as315-27.pdf"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2017.12.028"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2011.01.060"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf062820m"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7915.2012.00343.x"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.10725"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2006.11.001"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2010.10.014"},{"key":"e_1_2_6_35_1","first-page":"1210","volume-title":"Tratado de Enolog\u00eda I: Microbiolog\u00eda del vino","author":"Rib\u00e9reau\u2010Gayon P","year":"2003"},{"key":"e_1_2_6_36_1","first-page":"483","volume-title":"Foods and Beverages","author":"Wine EP","year":"1991"},{"key":"e_1_2_6_37_1","unstructured":"IOV IO of V and W.International code of oenological practices. OENO. 2021. p. 435."},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1106\/VFAT-5REN-1WK2-5JGQ"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.7b02762"},{"key":"e_1_2_6_40_1","first-page":"262","article-title":"Protection of aroma volatiles in a red wine with low Sulphur dioxide by a mixture of glutathione, caffeic acid and gallic acid","volume":"34","author":"Roussis IG","year":"2013","journal-title":"South African J Enol Vitic"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lwt.2007.03.018"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1080\/19440049.2016.1232864"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01218"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.3390\/fermentation4010006"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2015.10.034"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-0238.2005.tb00028.x"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lwt.2010.02.011"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.3390\/beverages4040091"}],"container-title":["Journal of the Science of Food and Agriculture"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jsfa.12209","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jsfa.12209","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jsfa.12209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T13:06:44Z","timestamp":1760879204000},"score":1,"resource":{"primary":{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/10.1002\/jsfa.12209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,23]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1002\/jsfa.12209"],"URL":"https:\/\/doi.org\/10.1002\/jsfa.12209","archive":["Portico"],"relation":{},"ISSN":["0022-5142","1097-0010"],"issn-type":[{"value":"0022-5142","type":"print"},{"value":"1097-0010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,23]]},"assertion":[{"value":"2022-04-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}