{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T02:18:38Z","timestamp":1791771518147,"version":"4.3.4"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,1,12]],"date-time":"2023-01-12T00:00:00Z","timestamp":1673481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31901687"],"award-info":[{"award-number":["31901687"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2023,3,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Fish skin gelatin (FSG) and luteolin (LUT) were used as composite emulsifiers, and benzyl isothiocyanate (BITC) was used as a model of nutrient delivery to construct a stable emulsion. The storage stability of the FSG\u2013LUT emulsion and its effect on BITC release were investigated both <jats:italic>in vitro<\/jats:italic> and <jats:italic>ex vivo<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>LUT can quench FSG fluorophores statically and form a stable complex through hydrogen bonding and hydrophobic interactions. The FSG\u2013LUT emulsion storage stability and embedding rate were higher than those of the FSG emulsion. The FSG\u2013LUT emulsion microstructure was resistant to oral and gastric digestion, and the BITC retention rate and bioaccessibility were much higher than those of the FSG emulsion. Lastly, the <jats:italic>ex vivo<\/jats:italic> everted gut sac of rat intestine study demonstrated that BITC showed the highest absorption in the ileum, and the FSG\u2013LUT emulsion absorbed BITC and sustained a controlled release in a specific position.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>LUT could form stable complexes with FSG, which improved the stability and bioavailability of BITC in the FSG\u2013LUT emulsion delivery system, and promoted further intestinal BITC absorption. \u00a9 2022 Society of Chemical Industry.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.12411","type":"journal-article","created":{"date-parts":[[2022,12,26]],"date-time":"2022-12-26T08:30:41Z","timestamp":1672043441000},"page":"1864-1873","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Construction of benzyl isothiocyanate\u2010loaded fish skin gelatin\u2010luteolin compound emulsion delivery system, and its digestion and absorption characteristics"],"prefix":"10.1002","volume":"103","author":[{"given":"Zhiyu","family":"Liu","sequence":"first","affiliation":[{"name":"National Engineering Research Center of Seafood, School of Food Science and Technology Dalian Polytechnic University  Dalian P. 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