{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:33:33Z","timestamp":1791228813144,"version":"4.1.0"},"reference-count":56,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T00:00:00Z","timestamp":1699228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100019340","name":"Nanning Science and Technology Base Project","doi-asserted-by":"publisher","award":["20212014"],"award-info":[{"award-number":["20212014"]}],"id":[{"id":"10.13039\/501100019340","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>In the present work, acute gastric ulcer models were constructed by administering hydrochloric acid\/ethanol. The mice ingested white jade snail secretion (WJSS) through gastric infusion. Ulcer areas in gastric tissue were recorded, and malondialdehyde (MDA) and superoxide dismutase (SOD) were also measured. Notably, high\u2010throughput 16S rDNA analysis of intestinal flora and determination of amino acid composition in feces were performed to understand the effect of WJSS on model mice.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Compared with the control group, the ulcer area in the WJSS low\u2010, medium\u2010 and high\u2010concentration groups declined by 28.02%, 39.57% and 77.85%, respectively. MDA content decreased by 24.71%, 49.58% and 64.25%, and SOD relative enzyme activity fell by 28.19%, 43.37% and 9.60%, respectively. The amounts of amino acids in the low\u2010, medium\u2010 and high\u2010concentration groups were slightly lower, and probiotic bacteria such as Bacteroidetes and Lactobacillales increased in different\u2010concentration WJSS groups. Adding WJSS contributes to the establishment of beneficial intestinal flora and the absorption of amino acids.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Our results showed that WJSS has a beneficial effect on inhibiting hydrochloric acid\u2013ethanolic gastric ulcers, suggesting that WJSS has excellent potential as a novel anti\u2010ulcer agent. Combined with ulcer area, MDA content, SOD content, gut probiotics and other indicators, a high concentration of WJSS had the best protective effect on acute gastric ulcer. \u00a9 2023 Society of Chemical Industry.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.13059","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T13:28:51Z","timestamp":1697635731000},"page":"1723-1731","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effect of white jade snail secretion on antioxidant capacity and intestinal microbial diversity in mouse model of acute gastric ulcer"],"prefix":"10.1002","volume":"104","author":[{"given":"Qian","family":"Cheng","sequence":"first","affiliation":[{"name":"Medical College Guangxi University  Nanning China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaidi","family":"Wang","sequence":"additional","affiliation":[{"name":"Medical College Guangxi 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