{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T03:49:54Z","timestamp":1785210594563,"version":"3.55.0"},"reference-count":65,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T00:00:00Z","timestamp":1716249600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32202687"],"award-info":[{"award-number":["32202687"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Bamboo leaf flavonoids (BLF) are the main bioactive ingredients in bamboo leaves. They have antioxidant, anti\u2010inflammatory, antibacterial, and other effects. In this study, the effects of dietary BLF on growth performance, immune response, antioxidant capacity, and intestinal microbiota of broilers were investigated. A total of 288 broilers were divided into three groups with eight replicates and 12 birds in each replicate. Broilers were fed a basic diet or the basic diet supplemented with 1000 or 2000\u2009mg\u2009kg<jats:sup>\u22121<\/jats:sup> BLF for 56\u2009days.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>The results showed that supplementation of BLF increased body weight (BW) and average daily weight gain (ADG), and reduced average daily feed intake (ADFI) (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The serum immunoglobulin A (IgA), immunoglobulin M (IgM), and interleukin 10 (IL\u201010) content of broilers in the BLF1000 group was increased and the interleukin 1<jats:italic>\u03b2<\/jats:italic> (IL\u20101<jats:italic>\u03b2<\/jats:italic>) and tumor necrosis factor\u2010<jats:italic>\u03b1<\/jats:italic> (TNF\u2010<jats:italic>\u03b1<\/jats:italic>) content was decreased (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The levels of IgM and IL\u201010 in jejunum mucosa were found to be enhanced by BLF (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The BLF1000 group exhibited a significant reduction in the concentration of TNF\u2010<jats:italic>\u03b1<\/jats:italic> (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). Serum and jejunum mucosa total antioxidant capacity (T\u2010AOC) levels in the BLF1000 group were increased (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The serum catalase (CAT) and glutathione peroxidase (GSH\u2010Px) effects of the BLF1000 group and serum CAT effects of BLF2000 group were increased (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The CON group demonstrated a lower relative abundance of <jats:italic>Christensenellaceae<\/jats:italic>_R\u20107_group and <jats:italic>Oscillibacter<\/jats:italic> than the BLF group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Dietary BLF inclusion enhanced the growth performance, immune, and antioxidant functions, improved the intestinal morphology, and ameliorated the intestinal microflora structure in broiler. Adding 1000\u2009mg\u2009kg<jats:sup>\u22121<\/jats:sup> BLF to the broiler diet can be considered as an effective growth promoter. \u00a9 2024 Society of Chemical Industry.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.13602","type":"journal-article","created":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T07:44:11Z","timestamp":1716277451000},"page":"7656-7667","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Effects of bamboo leaf flavonoids on growth performance, antioxidants, immune function, intestinal morphology, and cecal microbiota in broilers"],"prefix":"10.1002","volume":"104","author":[{"given":"Chao","family":"Wu","sequence":"first","affiliation":[{"name":"College of Animal Science and Technology, College of Veterinary Medicine, Key Laboratory of Applied Technology on Green\u2010Eco\u2010Healthy Animal Husbandry of Zhejiang Province Zhejiang Provincial Engineering Laboratory for Animal Health Inspection &amp; Internet Technology, Zhejiang Agricultural and Forestry University  Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Ma","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, College of Veterinary Medicine, Key Laboratory of Applied Technology on Green\u2010Eco\u2010Healthy Animal Husbandry of Zhejiang Province Zhejiang Provincial Engineering Laboratory for Animal Health Inspection &amp; Internet Technology, Zhejiang Agricultural and Forestry University  Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuwan","family":"Lu","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, College of Veterinary Medicine, Key Laboratory of Applied Technology on Green\u2010Eco\u2010Healthy Animal Husbandry of Zhejiang Province Zhejiang Provincial Engineering Laboratory for Animal Health Inspection &amp; Internet Technology, Zhejiang Agricultural and Forestry University  Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyan","family":"Shi","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, College of Veterinary Medicine, Key Laboratory of Applied Technology on Green\u2010Eco\u2010Healthy Animal Husbandry of Zhejiang Province Zhejiang Provincial Engineering Laboratory for Animal Health Inspection &amp; Internet Technology, Zhejiang Agricultural and Forestry University  Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinsong","family":"Liu","sequence":"additional","affiliation":[{"name":"Vegamax Green Animal Health products Key agricultural Enterprise Research Institute of Zhejiang Province Zhejiang Vegamax Biotechnology Co., Ltd  Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caimei","family":"Yang","sequence":"additional","affiliation":[{"name":"College of Animal Science and 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