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Among all the \u03b2C\u2010INU\u2010FA micelles, \u03b2C\u2010INU\u2010OA showed the strongest stability and homogeneity, with its encapsulation efficiency and loading capacity for \u03b2C reaching 62.26% and 0.251\u2009mg\u2009mg\n                      <jats:sup>\u22121<\/jats:sup>\n                      , respectively. It also showed good stability at 4 and 25\u2009\u00b0C. Co\u2010assembly molecular dynamics (MD) simulations confirmed that INU\u2010OA could encapsulate \u03b2C molecules by the strong van der Waals force provided by OA, resulting in stronger stability compared with unmodified INU. This superior performance of INU\u2010OA was attributed to its\n                      <jats:italic>cis<\/jats:italic>\n                      \u2010double\u2010bond\u2010induced bent conformation, which promoted a porous structure and enhanced hydrophobic interactions with \u03b2C, as evidenced by scanning electron microscopy and MD simulations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>This study combines macroscopic and microscopic analyses to demonstrate the potential of INU\u2010OA\u2010\u03b2C micelles as a promising \u03b2C delivery system, providing new insights for amphiphilic polysaccharide\u2010based carrier design. \u00a9 2026 Society of Chemical Industry.<\/jats:p>\n                  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