{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:11:22Z","timestamp":1786115482263,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T00:00:00Z","timestamp":1780790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T00:00:00Z","timestamp":1780790400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32372429"],"award-info":[{"award-number":["32372429"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>\n                      <jats:sc>l<\/jats:sc>\n                      \u2010Lysine (\n                      <jats:sc>l<\/jats:sc>\n                      \u2010Lys), an essential amino acid, serves as a core indicator for evaluating food nutritional quality. Although naturally abundant in ingredients such as soybeans, its content must be precisely regulated during processing to meet nutritional standards. Moreover, improper processing and storage can induce\n                      <jats:sc>l<\/jats:sc>\n                      \u2010Lys degradation or conversion, compromising both nutritional value and food safety. Given its pivotal role in nutritional balance and quality assurance, there is an urgent need for simple, rapid, and highly sensitive analytical methods for\n                      <jats:sc>l<\/jats:sc>\n                      \u2010Lys detection.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      An innovative \u2018off\u2013on\u2019 fluorescent sensor tailored for food\u2010related applications was developed, utilizing CdTe quantum dots as the fluorophore and dodecyl trimethyl ammonium bromide self\u2010assembled citrate\u2010capped gold nanoparticles (DTAB\u2010AuNPs) as the quencher for the rapid detection of\n                      <jats:sc>l<\/jats:sc>\n                      \u2010lys. During the detection process,\n                      <jats:sc>l<\/jats:sc>\n                      \u2010lys served as a binding bridge, facilitating the aggregation of DTAB\u2010AuNPs. This reduction inhibited fluorescence resonance energy transfer between the fluorophore and the quencher, leading to fluorescence recovery. The degree of aggregation\u2010induced fluorescence recovery exhibited a linear correlation with the concentration of\n                      <jats:sc>l<\/jats:sc>\n                      \u2010lys within the range of 0.5\u201310\u2009\u03bc\n                      <jats:sc>m<\/jats:sc>\n                      (\n                      <jats:italic>R<\/jats:italic>\n                      \u2009=\u20090.999). This newly developed sensing method demonstrated an impressive limit of detection of 3.22\u2009n\n                      <jats:sc>m<\/jats:sc>\n                      . It was successfully applied to detect\n                      <jats:sc>l<\/jats:sc>\n                      \u2010lys in various food\u2010relevant samples, including milk, soybean, plasma and compound amino acid oral solution used in food\u2010related nutritional supplements.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>The results highlight its great potential for practical applications in multiple fields such as quality control of dairy and agricultural products, as well as clinical diagnosis related to nutritional status assessment. \u00a9 2026 Society of Chemical Industry.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jsfa.70784","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T03:51:39Z","timestamp":1780890699000},"page":"7416-7425","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A novel fluorescent sensor based on\n                    <scp>CdTe<\/scp>\n                    quantum dots and\n                    <scp>DTAB<\/scp>\n                    \u2010modified Au nanoparticles through aggregation\u2010induced fluorescence recovery for the detection of\n                    <scp>l<\/scp>\n                    \u2010lysine"],"prefix":"10.1002","volume":"106","author":[{"given":"Xinyi","family":"Min","sequence":"first","affiliation":[{"name":"The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences South\u2010Central Minzu University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zhao","sequence":"additional","affiliation":[{"name":"The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences South\u2010Central Minzu University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhang","family":"Xiao","sequence":"additional","affiliation":[{"name":"The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences South\u2010Central Minzu University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyu","family":"Zhao","sequence":"additional","affiliation":[{"name":"The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences South\u2010Central Minzu University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaner","family":"Zhao","sequence":"additional","affiliation":[{"name":"The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences South\u2010Central Minzu University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilinigaer","family":"Wumaier","sequence":"additional","affiliation":[{"name":"The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences South\u2010Central Minzu University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dajuan","family":"Dai","sequence":"additional","affiliation":[{"name":"The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences South\u2010Central Minzu University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hengye","family":"Chen","sequence":"additional","affiliation":[{"name":"The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences South\u2010Central Minzu University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4219-1009","authenticated-orcid":false,"given":"Wanjun","family":"Long","sequence":"additional","affiliation":[{"name":"The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences South\u2010Central Minzu University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6914-5281","authenticated-orcid":false,"given":"Wei","family":"Lan","sequence":"additional","affiliation":[{"name":"The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences South\u2010Central Minzu University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0865-0652","authenticated-orcid":false,"given":"Haiyan","family":"Fu","sequence":"additional","affiliation":[{"name":"The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, School of Pharmaceutical Sciences South\u2010Central Minzu University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12896-024-00838-5"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2025.343914"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40364-024-00621-w"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1210\/endrev\/bnaa026"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2022.121453"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2023.115390"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.2c01325"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.109307"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2023.109363"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/ma13081999"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.measurement.2023.113468"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2019.112812"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2016.01.024"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2025.116672"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2024.125502"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29061304"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.4c04172"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.microc.2022.107666"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2025.344617"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10895-024-03997-y"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2023.108426"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2025.128045"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2022.131792"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2022.107846"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfa.2025.136969"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2024.126972"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2023.143103"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00604-022-05608-8"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2021.120701"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2006.08.005"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.microc.2024.110508"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/451232"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2010.02.032"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2017.12.060"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2019.117803"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23168985"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpc.2024.107238"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2021.07.010"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.microc.2025.116689"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5RA00621J"}],"container-title":["Journal of the Science of Food and Agriculture"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jsfa.70784","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jsfa.70784","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jsfa.70784","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T03:13:51Z","timestamp":1785986031000},"score":1,"resource":{"primary":{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/10.1002\/jsfa.70784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,7]]},"references-count":40,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/jsfa.70784"],"URL":"https:\/\/doi.org\/10.1002\/jsfa.70784","archive":["Portico"],"relation":{},"ISSN":["0022-5142","1097-0010"],"issn-type":[{"value":"0022-5142","type":"print"},{"value":"1097-0010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,7]]},"assertion":[{"value":"2025-10-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}