{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:56:20Z","timestamp":1791561380721,"version":"4.3.4"},"reference-count":52,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>\n                      This study investigated the effects of\n                      <jats:italic>Thymus vulgaris (<\/jats:italic>\n                      TV\n                      <jats:italic>)<\/jats:italic>\n                      enrichment on the phytochemical profile, antioxidant capacity, antimicrobial activity, amino acid composition, and \u03b1\u2010glucosidase inhibitory potential of fermented dairy\u2010based tarhana. Tarhana was produced in three formulations (control, 40\u2009g\u2009kg\n                      <jats:sup>\u22121<\/jats:sup>\n                      (TV4), and 80\u2009g\u2009kg\n                      <jats:sup>\u22121<\/jats:sup>\n                      (TV8) thyme enrichment) under controlled fermentation and drying conditions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      The results showed that TV integration significantly increased total phenolic content (TPC) and total flavonoid content (TFC) in a dose\u2010dependent manner, leading to superior DPPH and ABTS radical scavenging activities. Microbiological analysis revealed a selective antimicrobial effect; TV effectively suppressed yeast and mould growth while maintaining the viability of lactic acid bacteria (LAB), ensuring fermentation integrity. Specifically, TV enrichment increased nutrient density, raising total free amino acids from 1821.7\u2009\u03bcg\u2009g\n                      <jats:sup>\u22121<\/jats:sup>\n                      to 2803.6\u2009\u03bcg\u2009g\n                      <jats:sup>\u22121<\/jats:sup>\n                      . Liquid chromatography\u2013tandem mass spectrometry (LC\u2013MS\/MS) analysis identified a robust bioactive profile, including rosmarinic acid, luteolin, and naringenin. The TV8 group exhibited a strong antidiabetic profile, providing approximately 90% inhibition of \u03b1\u2010glucosidase. Molecular docking confirmed that TV\u2010derived ligands exhibited high binding affinities in the catalytic pockets of metabolic enzymes, mimicking or exceeding the stability of standard inhibitors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>The results demonstrate that thyme enrichment enhances the functional and bioactive properties of fermented dairy\u2010based tarhana, offering a scientifically supported strategy for developing value\u2010added functional dairy products with potential metabolic health benefits. \u00a9 2026 Society of Chemical Industry.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jsfa.70845","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T03:53:21Z","timestamp":1782186801000},"page":"8363-8378","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Functional enhancement of fermented dairy\u2010based tarhana with\n                    <i>Thymus vulgaris<\/i>\n                    : phytochemical characterisation and\n                    <scp>\n                      <i>in vitro<\/i>\n                    <\/scp>\n                    antidiabetic potential"],"prefix":"10.1002","volume":"106","author":[{"given":"Serap K\u0131l\u0131\u00e7","family":"Altun","sequence":"first","affiliation":[{"name":"Department of Food Hygiene and Technology, Faculty of Veterinary Medicine Harran University  \u015eanl\u0131urfa 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