{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T18:14:39Z","timestamp":1768414479103,"version":"3.49.0"},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,4,23]],"date-time":"2015-04-23T00:00:00Z","timestamp":1429747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100014935","name":"Suncheon Research Center for Natural Medicines","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100014935","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p><jats:italic>Salicornia herbacea L<\/jats:italic>. is a halophyte that grows in salt marshes and contains significant amounts of salts and minerals. Because it is known as a folk medication to treat diseases, various processed products such as powder, globular type of powder, laver and extract have been developed. However, it is difficult to process as a drink because of its high salinity. In the present study, glasswort vinegar (<jats:styled-content style=\"fixed-case\">GV<\/jats:styled-content>) containing high amounts of organic acids and minerals was developed via two\u2010step fermentation with unpolished rice substrates and investigated its antioxidant and anti\u2010fatigue activities.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">GV<\/jats:styled-content> showed various free radical scavenging effects, reducing power, oxidized\u2010<jats:styled-content style=\"fixed-case\">LDL<\/jats:styled-content> inhibition and superoxide dismutase\u2010like activities. Compared with the control group (orally administered 7 g kg<jats:sup>\u22121<\/jats:sup> distilled water), the <jats:styled-content style=\"fixed-case\">GV<\/jats:styled-content> supplementation group showed increased running endurance and had higher glycogen accumulation in liver and muscles of rats exhausted by exercise. Furthermore, the <jats:styled-content style=\"fixed-case\">GV<\/jats:styled-content>\u2010administered group demonstrated significantly elevated lactate and <jats:styled-content style=\"fixed-case\">ATP<\/jats:styled-content> metabolism, promoting enzyme activities such as muscle creatine kinase and lactate dehydrogenase, whereas serum fatigue biomarkers such as ammonia, lactate and inorganic acid were markedly decreased.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>These results indicate that <jats:styled-content style=\"fixed-case\">GV<\/jats:styled-content> can be used as a functional food for the development of a dietary beverage to alleviate fatigue. \u00a9 2015 Society of Chemical Industry<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.7180","type":"journal-article","created":{"date-parts":[[2015,3,19]],"date-time":"2015-03-19T13:53:55Z","timestamp":1426773235000},"page":"1085-1092","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Production of novel vinegar having antioxidant and anti\u2010fatigue activities from <i>Salicornia herbacea<\/i> L."],"prefix":"10.1002","volume":"96","author":[{"given":"Hyun\u2010Dong","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Food and Nutrition Sunchon National University  Suncheon 540\u2010950 Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ju\u2010Hye","family":"Lee","sequence":"additional","affiliation":[{"name":"Research Institute of Basic Science Sunchon National University  Suncheon 540\u2010950 Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji\u2010Hye","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition Sunchon National University  Suncheon 540\u2010950 Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae\u2010Yong","family":"Kim","sequence":"additional","affiliation":[{"name":"Jeonnam Institute of natural resources research  Jangheung 529\u2010851 Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung\u2010Tae","family":"Yee","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Sunchon National University  Suncheon 540\u2010950 Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seok\u2010Kyu","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition Sunchon National University  Suncheon 540\u2010950 Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi\u2010Kyung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition Sunchon National University  Suncheon 540\u2010950 Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwon\u2010Il","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition Sunchon National University  Suncheon 540\u2010950 Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201200529"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2012.05.017"},{"key":"e_1_2_6_4_1","first-page":"93","article-title":"Studies on pharmacological effects of glasswort (Salicornia herbacea L.)","volume":"10","author":"Jo YC","year":"2002","journal-title":"Korean J Med Crop Sci"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.3746\/jkfn.2008.37.9.1196"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.4162\/nrp.2007.1.4.371"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3746\/jkfn.2006.35.1.055"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.3746\/jkfn.2002.31.5.840"},{"key":"e_1_2_6_9_1","first-page":"216","article-title":"Chemical constitutes of native plant","volume":"15","author":"Shin KS","year":"2002","journal-title":"Salicornia herbacea L. 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