{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:24:41Z","timestamp":1788315881980,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,5,12]],"date-time":"2015-05-12T00:00:00Z","timestamp":1431388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Broilers are vulnerable to various types of microorganisms, including <jats:italic>Salmonella<\/jats:italic>, <jats:italic>Escherichia coli<\/jats:italic> and <jats:italic>Staphylococcus aureus<\/jats:italic>, resulting in multiple infections. Broad\u2010spectrum antibacterial drugs such as florfenicol (<jats:styled-content style=\"fixed-case\">FF<\/jats:styled-content>) are widely used in the treatment of such infections. Suspected residues of these drugs in body tissues of treated birds can be passed to humans through meat consumption and thus lead to serious ill effects on human health. The present study was designed to estimate the presence of <jats:styled-content style=\"fixed-case\">FF<\/jats:styled-content> residues in broiler meat and liver samples.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>The mean residual concentrations of <jats:styled-content style=\"fixed-case\">FF<\/jats:styled-content> in broiler meat and liver samples were 311.42\u2009\u00b1\u2009186.56 and 2585.44\u2009\u00b1\u20091759.71\u2009\u00b5g\u2009kg<jats:sup>\u22121<\/jats:sup> respectively, which are higher than their respective maximum residual limits (<jats:styled-content style=\"fixed-case\">MRLs<\/jats:styled-content>). The results showed that 126 and 24 samples were <jats:styled-content style=\"fixed-case\">FF<\/jats:styled-content>\u2010positive and <jats:styled-content style=\"fixed-case\">FF<\/jats:styled-content>\u2010negative respectively. Of the positive samples, 84 and 42 samples were above and below the <jats:styled-content style=\"fixed-case\">MRL<\/jats:styled-content> respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>The results indicate the presence of <jats:styled-content style=\"fixed-case\">FF<\/jats:styled-content> residues in broiler meat and liver samples. Usage of this contaminated meat causes resistance in consumers and poses a public health threat. Thus there is a need to educate farmers about the ill effects of residual drugs on human health and their withdrawal times in poultry. \u00a9 2015 Society of Chemical Industry<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.7220","type":"journal-article","created":{"date-parts":[[2015,4,17]],"date-time":"2015-04-17T03:45:06Z","timestamp":1429242306000},"page":"1284-1288","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Determination of florfenicol residues in broiler meat and liver samples using RP\u2010HPLC with UV\u2013visible detection"],"prefix":"10.1002","volume":"96","author":[{"given":"Asma","family":"Nasim","sequence":"first","affiliation":[{"name":"Department of Physiology and Pharmacology University of Agriculture  Faisalabad 38040 Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilal","family":"Aslam","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pharmacology University of Agriculture  Faisalabad 38040 Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ijaz","family":"Javed","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pharmacology University of Agriculture  Faisalabad 38040 Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asghar","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pharmacology University of Agriculture  Faisalabad 38040 Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faqir","family":"Muhammad","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pharmacology University of Agriculture  Faisalabad 38040 Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Raza","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pharmacology University of Agriculture  Faisalabad 38040 Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zia\u2010ud\u2010Din","family":"Sindhu","sequence":"additional","affiliation":[{"name":"Department of Parasitology University of Agriculture  Faisalabad 38040 Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,5,12]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"19","article-title":"The production and consumption of livestock foods in Pakistan: a look into the future","volume":"33","author":"Akmal M","year":"2013","journal-title":"Pak Dev Rev"},{"issue":"7","key":"e_1_2_6_3_1","first-page":"42","article-title":"A retrospective study (2000\u20132005) of poultry diseases diagnosed at Department of Avian Diseases & Diagnosis, Veterinary Research Institute (VRI)\u2010Khartoum, Sudan","volume":"9","author":"Khalifa KA","year":"2013","journal-title":"J Am Sci"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkg483"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1086\/340246"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-79382-5_16"},{"issue":"12","key":"e_1_2_6_7_1","first-page":"514","article-title":"Residue withdrawal of florfenicol from the serum and edible tissues of broiler chicken","volume":"8","author":"Khalil S","year":"2012","journal-title":"J Am Sci"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/19440049.2013.781685"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540105.2012.753513"},{"key":"e_1_2_6_10_1","first-page":"25","article-title":"Screening of chloramphenicol residues in broiler chickens slaughtered in an industrial poultry abattoir in Mashhad, Iran","volume":"2","author":"Mehdizadeh S","year":"2010","journal-title":"Iranian J Vet Sci Technol"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps.2011-01564"},{"key":"e_1_2_6_12_1","first-page":"25","article-title":"Issues and economics of poultry production: a case study of Faisalabad","volume":"27","author":"Abedullah MA","year":"2007","journal-title":"Pakistan. 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