{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T13:23:40Z","timestamp":1773753820025,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2016,3,10]],"date-time":"2016-03-10T00:00:00Z","timestamp":1457568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31460538"],"award-info":[{"award-number":["31460538"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Sci Food Agric"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Macamides with a benzylalkylamide nucleus are characteristic and major bioactive compounds in the functional food maca (<jats:italic>Lepidium meyenii<\/jats:italic> Walp). The aim of this study was to explore variations in macamide content among maca from China and Peru. Twenty\u2010seven batches of maca hypocotyls with different phenotypes, sampled from different geographical origins, were extracted and profiled by liquid chromatography with ultraviolet detection\/tandem mass spectrometry (LC\u2010UV\/MS\/MS).<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Twelve macamides were identified by MS operated in multiple scanning modes. Similarity analysis showed that maca samples differed significantly in their macamide fingerprinting. Partial least squares discriminant analysis (PLS\u2010DA) was used to differentiate samples according to their geographical origin and to identify the most relevant variables in the classification model. The prediction accuracy for raw maca was 91% and five macamides were selected and considered as chemical markers for sample classification.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>When combined with a PLS\u2010DA model, characteristic fingerprinting based on macamides could be recommended for labelling for the authentication of maca from different geographical origins. The results provided potential evidence for the relationships between environmental or other factors and distribution of macamides. \u00a9 2016 Society of Chemical Industry<\/jats:p><\/jats:sec>","DOI":"10.1002\/jsfa.7660","type":"journal-article","created":{"date-parts":[[2016,2,9]],"date-time":"2016-02-09T03:54:36Z","timestamp":1454990076000},"page":"4475-4483","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Characteristic fingerprinting based on macamides for discrimination of maca (<i>Lepidium meyenii<\/i>) by LC\/MS\/MS and multivariate statistical analysis"],"prefix":"10.1002","volume":"96","author":[{"given":"Yu","family":"Pan","sequence":"first","affiliation":[{"name":"Institute of Medicinal Plants Yunnan Academy of Agricultural Sciences  Kunming 650200 China"},{"name":"Yunnan Technical Center for Quality of Chinese Materia Medica  Kunming 650200 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